U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 121 - 130 of 2365 results

Status:
Investigational
Source:
INN:nifuraldezone
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Nifuraldezone is an antibacterial compound. It completely mimics the radiosensitizing effect of molecular oxygen in hypoxic mammalian cells in vitro at concentrations in tissue culture medium which showed no measurable acute toxicity.
Status:
Investigational
Source:
INN:nifurdazil
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Nifurdazil, a 5-nitrofuran derivative, ia an antibacterial agent.

Class (Stereo):
CHEMICAL (ACHIRAL)

Naphthol Blue Black is a dye, used for the staining of western blot membrane for detection of all protein that are transferred to the membrane. It is also can be used as nucleic acid stain in SDS-Page gels.
U0126 is a highly selective inhibitor of both MEK1 and MEK2, a type of MAPK/ERK kinase. The inhibitory effects of U0126 on MEK and ERK activation have been confirmed repeatedly, and treatments with U0126 have been shown to inhibit proliferation and migration of cancer cells in vivo and in vitro. U0126 has been widely used as an inhibitor for the Ras/Raf/MEK/ERK signaling pathway. U0126 treatments lead to cancer cell death, which agrees with the well-known role of the Ras/Raf/MEK/ERK pathway in supporting cell survival. U0126 enhances apoptosis in human breast cancer MCF-7 cells, acute myeloid leukemia, and PC12 cells.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)