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Search results for phenyl root_names_stdName in Standardized Name (approximate match)
Status:
Other
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
(-)-vesamicol is an active enantiomer of vesamicol (AH5183 or [(-)-trans-2-(4-phenylpiperidino)cyclohexanol]). It inhibits the uptake of acetylcholine into cholinergic neuronal storage vesicles. Vesicular acetylcholine transporter (VAChT) is inhibited by (-)-vesamicol, which binds tightly to an allosteric site.
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
BIBO-3304 is a subtype selective nonpeptide antagonist with subnanomolar affinity for the Y1 receptor subtype that significantly inhibits food intake induced by application of NPY or by fasting. BIBO-3304 is a NPY Y1 receptor antagonist (IC50 values are 0.38 and 0.72 nM at human and rat receptors respectively) that displays > 2600-fold selectivity over Y2, Y4 and Y5 receptors.
