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Development Status
Other
640
Possibly Marketed Outside US
157
Investigational
148
US Approved Rx
101
US Previously Marketed
55
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Primary Target
Histamine H1 receptor
10
Dopamine D2 receptor
9
Serotonin 2a (5-HT2a) receptor
7
Estrogen receptor beta
6
Estrogen receptor alpha
5
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Highest Phase
Approved
125
Phase II
14
Phase III
14
Phase I
5
Phase IV
1
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Approval Year
Unknown
829
1921
37
2012
15
2010
13
2009
12
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Condition
Hypertension
12
Unknown
11
Schizophrenia
9
Alzheimer’s disease
7
Cancer
7
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Treatment Modality
Primary
144
Curative
27
Palliative
27
Preventing
24
Diagnostic
8
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CNS Activity
CNS Active
60
CNS Penetrant
51
CNS Non-penetrant
23
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Originator
Eli Lilly
9
Novartis
9
AstraZeneca
5
Merck
5
GlaxoSmithKline
4
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Substance Class
Chemical
666
Structurally Diverse
209
Protein
193
Concept
33
Mixture
14
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INN Stem
Chemical substance(-ine)
5
Peptides and glycopeptides(-tide)
3
Antiviral drug(-vir)
1
Tyrosine-kinase inhibitors(-tinib)
1
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GInAS Tag
KEW
13
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Code System
FDA UNII
1,100
CAS
733
PUBCHEM
658
EPA CompTox
415
NCI_THESAURUS
350
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Protein Type
ENZYME
27
RECEPTOR
27
PEPTIDE
16
MONOCLONAL ANTIBODY
8
CYTOKINE
4
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ATC Level 1
NERVOUS SYSTEM
26
ALIMENTARY TRACT AND METABOLISM
25
CARDIOVASCULAR SYSTEM
19
ANTIINFECTIVES FOR SYSTEMIC USE
16
RESPIRATORY SYSTEM
12
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ATC Level 2
ANTIBACTERIALS FOR SYSTEMIC USE
10
PSYCHOANALEPTICS
10
PSYCHOLEPTICS
9
OPHTHALMOLOGICALS
8
AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
6
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ATC Level 3
ANTIDEPRESSANTS
8
ANTIHISTAMINES FOR SYSTEMIC USE
6
ANTIPSYCHOTICS
6
CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
4
DIRECT ACTING ANTIVIRALS
4
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ATC Level 4
Antibiotics
5
Diazepines, oxazepines, thiazepines and oxepines
4
Non-selective monoamine reuptake inhibitors
4
Other antihistamines for systemic use
4
ACE inhibitors and calcium channel blockers
3
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Substance Form
Principal Form
1,036
Salts, Hydrates, Esters, etc.
64
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Search results for
m root_references_citation
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JNJ-40929837
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R5CDF0LNV3
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Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
V-116517
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TBJ73RQT8F
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Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
RODATRISTAT
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91D8378G2V
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Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
PSMA-1007 F-18
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F1CB00L2RH
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Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
ISOREMOXIPRIDE C-11
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8PK3XYY6EX
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Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
SB-773812
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ZNP5SNF9FY
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Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
5-CNAC
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QG2TQ56MD1
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Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
VEBICORVIR
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16F6055SMG
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Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
TBI-166
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TY9R7N6MS5
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Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
SATOREOTIDE TETRAXETAN
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EC1O2FB9FV
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Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
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