Inxight Drugs

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Primary Target

neuromuscular synaptic transmission

2

Histamine H1 receptor

316

Dopamine D2 receptor

311

DNA

282

Serotonin 2a (5-HT2a) receptor

237

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Possibly Marketed Outside US

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Nematode Infections

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Curative

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Originator

Imperial Chemical Industries

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Showing 1 - 2 of 2 results

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METYRIDINE

08760H16R0

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Status:

Possibly Marketed Outside US

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

neuromuscular synaptic transmission

Conditions:

Nematode Infections

Metyridine has been shown to possess anthelmintic activity, particularly for the nematodes of the alimentary canal. Methyridine is able to pass freely through most of the barriers, which maintain body integrity. It produces neuromuscular block of the...

decamethonium type. There appears to be sufficient difference between the sensitivity of nematode and vertebrate nervous systems to this drug to allow a wide safety margin for its use in animals. Signs of toxicity, principally dullness and lassitude, may be produced by overdosage of the drug. When given subcutaneously methyridine may cause local pain, and swelling.

METHYRIDINE SULFATE

JIE9060WXN

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Status:

Possibly Marketed Outside US

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

neuromuscular synaptic transmission

Conditions:

Nematode Infections

Metyridine has been shown to possess anthelmintic activity, particularly for the nematodes of the alimentary canal. Methyridine is able to pass freely through most of the barriers, which maintain body integrity. It produces neuromuscular block of the...

decamethonium type. There appears to be sufficient difference between the sensitivity of nematode and vertebrate nervous systems to this drug to allow a wide safety margin for its use in animals. Signs of toxicity, principally dullness and lassitude, may be produced by overdosage of the drug. When given subcutaneously methyridine may cause local pain, and swelling.

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