Showing 1 - 2 of 2 results
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Palosuran, also known as ACT-058362, a potent and specific antagonist of
the human UT receptor. Urotensin inhibition with palosuran was a promising alternative in pulmonary arterial hypertension. Palosuran inhibits binding to primate UT receptors in ...
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
SB-706375 is a potent, surmountable, reversible and selective mammalian urotensin-II receptor antagonist. In rats SB-706375 provoked a pronounced diuresis and natriuresis, accompanied by modest increases in effective renal blood flow and glomerular ...