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Primary Target
Norepinephrine transporter
191
Histamine H1 receptor
315
Dopamine D2 receptor
297
DNA
278
Bacterial penicillin-binding protein
233
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Development Status
US Approved Rx
91
Other
56
Investigational
21
Possibly Marketed Outside US
11
US Previously Marketed
8
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Highest Phase
Approved
110
Phase III
6
Phase I
4
Not Provided
2
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Approval Year
Unknown
88
2008
14
1937
12
1959
10
1961
10
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Condition
Major depressive disorder
32
Attention deficit hyperactivity disorder
20
Depression
20
Unknown
17
Moderate to severe binge eating disorder
12
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Treatment Modality
Primary
130
Palliative
4
Preventing
2
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CNS Activity
CNS Active
118
CNS Penetrant
7
CNS Non-penetrant
3
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Originator
Smith Kline & French Laboratories
12
Wyeth
12
Niemann, A.
8
Eli Lilly
7
DOV Pharmaceutical
6
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Substance Class
Chemical
191
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INN Stem
Chemical substance(-ine)
1
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Code System
FDA UNII
191
PUBCHEM
191
CAS
186
EPA CompTox
138
SMS_ID
110
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ATC Level 1
NERVOUS SYSTEM
23
ALIMENTARY TRACT AND METABOLISM
3
SENSORY ORGANS
3
RESPIRATORY SYSTEM
2
CARDIOVASCULAR SYSTEM
1
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ATC Level 2
PSYCHOANALEPTICS
19
ANALGESICS
3
ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
3
OPHTHALMOLOGICALS
3
ANESTHETICS
1
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ATC Level 3
ANTIDEPRESSANTS
15
PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
4
ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
3
ANTIGLAUCOMA PREPARATIONS AND MIOTICS
2
OPIOIDS
2
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ATC Level 4
Non-selective monoamine reuptake inhibitors
8
Other antidepressants
6
Centrally acting sympathomimetics
4
Centrally acting antiobesity products
3
Other antiglaucoma preparations
2
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Substance Form
Salts, Hydrates, Esters, etc.
115
Principal Form
76
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Primary Target
Norepinephrine transporter
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