Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Tizoxanide, the primary active metabolite of the FDA approved drug nitazoxanide, an anti-infective that has been approved for the treatment of diarrhea caused by Giardia lamblia. Tizoxanide, an active metabolite of nitazoxanide in humans, is also an ...
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. When administered concomittantly with levodopa and a decarboxylase inhibitor...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Streptomycin is a water-soluble aminoglycoside derived from Streptomyces griseus. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its gr...
Thiazosulfone (also known as Promizole) is a phenylsulfonylthiazole derivative patented by Parke, Davis & Co. as the anti-tuberculosis agent. In preclinical models, Thiazosulfone exerts a definitely favorable influence on the course of experiment...
Thiambutosine is a carbanilide derivative patented by Imperial Chemical Industries Ltd. as the antituberculous agent. In vitro, the resistance of Mycobacterium tuberculosis H37Rv to Thiambutosine develops more slowly than resistance to streptomycin, ...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Cetylamine is an aliphatic primary amine that possesses surface-active properties and widely used in water treatment. Cetylamine shows moderate anti-tuberculosis activity. Cetylamine also may be used as a source of fluoride in the prevention of dent...
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Picromycin was studied by Brokmann and Hekel in 1951 and was the first antibiotic macrolide to be isolated. Picromycin is not a clinically useful antibiotic, it can be used as a raw material to synthesize antibiotic ketolide compounds such as ertythr...
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Nidulin is a depsidone produced by several fungal species with potent and selective antibacterial activity. Nidulin revealed a potent aromatase inhibitory activity.
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Cloxyquin has being shown to be a novel activator of the two-pore domain
potassium channel TRESK, which is linked to causing migraines and controls the sensitivity of pain nerves in the brain.