Showing 1 - 6 of 6 results
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Orlistat or tetrahydrolipstatin (Xenical, Hoffmann-La Roche) is a saturated derivative of lipstatin originally isolated from Streptomyces toxytricini. Orlistat (Xenical, Hoffmann-La Roche) is a powerful inhibitor of gastrointestinal lipase and as suc...
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Pyrazinamide is indicated for the initial treatment of active tuberculosis in adults and children when combined with other antituberculous agents. (The current recommendation of the CDC for drug-susceptible disease is to use a six-month regimen for i...
Status:
Other
Class (Stereo):
CHEMICAL (MIXED)
Conditions:
Tetrahydro-4-Methylene-2-octyl-5-oxo-3-furancarboxylic acid or C75 is an inhibitor of fatty acid synthase. Additionally, C75 increased fatty acid oxidation and ATP levels by increasing carnitine palmitoyltransferase I (CPT I) activity. Unlike the act...
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Cerulenin ((2R,3S)-2,3-epoxy-4-oxo-7,10-trans, trans-dodecadienoylamide) is an antifungal antibiotic isolated from Cephalosporium caerulens, that inhibits eukaryotic lipid and sterol synthesis and blocks lipid modification of proteins. Cerulenin is a...
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Nimbin is the active compound from the neem leaf extract which is now being tested in silico as a potential remedy against tuberculosis and dengue virus. Recent studies have shown that the drug interacts with NS2B-NS3 protease from dengue virus and f...