Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Aplindore (DAB-452) is a small molecule that displays potent dopamine D2 receptor partial agonist activity in in vitro and in vivo assays and is predicted to have antipsychotic efficacy without motor side effects. Aplindore had been in phase II clini...
Class (Stereo):
CHEMICAL (ACHIRAL)
Fananserin is a potential antipsychotic compound with a high affinity for both D4 and 5-HT2A receptors, and negligible affinity for D2 receptors. Fananserin has been researched for the treatment of schizophrenia. Fananserin was the first selective D4...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Sonepiprazole exhibits highly specific binding
to the D4 dopamine receptor with more than 100-fold
selectivity for the D4 receptor over other receptors, including
dopamine, serotonin, and adrenergic receptors. It is a neutral antagonist at the D4 dop...
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
CP 226269 is a selective dopamine D4 agonist. This compound was developed by Pfizer for Neuroscience research. CP226269 showed a significant enhancement in the 5-trial inhibitory avoidance model.
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Other
Class (Stereo):
CHEMICAL (RACEMIC)