L-741,626

OC1(CCN(CC2=CNC3=C2C=CC=C3)CC1)C4=CC=C(Cl)C=C4

InChIKey=LLBLNMUONVVVPG-UHFFFAOYSA-N

InChI=1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
Dopamine D2 receptor 311 Target ID: CHEMBL217 Sources: https://www.ncbi.nlm.nih.gov/pubmed/8642550 \| https://www.ncbi.nlm.nih.gov/pubmed/9833627	Antagonist 2849	2.4 nM [Ki]
Dopamine D3 receptor 97 Target ID: CHEMBL234 Sources: https://www.ncbi.nlm.nih.gov/pubmed/8642550	Antagonist 2849	100.0 nM [Ki]
Dopamine D4 receptor 76 Target ID: CHEMBL219 Sources: https://www.ncbi.nlm.nih.gov/pubmed/8642550 \| https://www.ncbi.nlm.nih.gov/pubmed/9833627	Antagonist 2849	220.0 nM [Ki]

Substance Class	Chemical Created by `admin` on `Tue Apr 01 16:21:53 GMT 2025` Edited by `admin` on `Tue Apr 01 16:21:53 GMT 2025`
Record UNII	WTW4A6SW92
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

L-741,626

Code

English

3-(4-(4-CHLOROPHENYL-4-HYDROXYPIPERIDINO)METHYL)INDOLE

Preferred Name

English

L-741

Code

English

4-(4-Chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol

Systematic Name

English

4-Piperidinol, 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)-

Systematic Name

English

L-741626

Code

English

Code System Code Type Description

PUBCHEM

133633