Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Harmine (aka telepathine) is a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds. It is a naturally occurring metabolite in a number of plants, notably the Middle Eastern plant harmal or Syrian rue (Peganum harmala) and...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Clorgiline is a monoamine oxidase (MAO) inhibitor. Specifically, it is an irreversible and selective inhibitor of MAO-A. Clorgiline was under investigation for antidepressant and anxiolytic potential but has never been marketed, likely due to efficac...
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Salsoline is a metabolite of dopamine and is highly prevalent in the urine and cerebrospinal fluid of alcoholics at the time of intoxication and for several days after. Salsoline and related compounds bind to the Type A Mono-amine Oxidase inducing n...
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Nialamide is a non-selective, irreversible monoamine oxidase inhibitor of the hydrazine class. It was previously used as an antidepressant (trade name Niamid) but was withdrawn by Pfizer in 1963 due to the risk of hepatotoxicity.
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Iproniazid is a non-selective, irreversible monoamine oxidase inhibitor (MAO) of the hydrazine class. It was originally developed for the treatment of Tuberculosis, but in 1952, its antidepressant properties were discovered when researchers noted tha...
Class (Stereo):
CHEMICAL (ACHIRAL)
Eprobemide (brand name Befol/Бефол), a drug used in Russia, is a selective, reversible monoamine oxidase A (MAO) inhibitor, which causes deamination of noradrenaline, serotonin, partially dopamine and β-phenylethylamine, thus increases the content of...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Amezinium is a sympathomimetic used for its vasopressor effects in the treatment of hypotensive states. Amezinium inhibited monoamine oxidase (MAO) activity. Amezinium antagonized the response to tyramine and blocked neuronal uptake of noradrenaline....
Class (Stereo):
CHEMICAL (ACHIRAL)
Caroxazone, 2-oxo-2H-1,3-benzoxazine-3(4H)-acetamide, was a psychotropic agent which in clinical studies was shown to possess a relevant antidepressant activity and was used to treat depression. This drug acts as a reversible inhibitor on both monoam...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Indoles and their derivatives are well-known as an important class of heterocyclic compounds, their core being a near-ubiquitous component of biologically active natural products, widespread in different species of plants, animals, and marine organis...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Clorgiline is a monoamine oxidase (MAO) inhibitor. Specifically, it is an irreversible and selective inhibitor of MAO-A. Clorgiline was under investigation for antidepressant and anxiolytic potential but has never been marketed, likely due to efficac...