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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
AZD-1283 is an antagonist of P2Y12 receptor which was developed by AstraZeneca for the treatment of arterial thrombosis. The drug was tested in pre-clinical studies, however its develoment was terminated.
Status:
Other
Class (Stereo):
CHEMICAL (RACEMIC)
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
SB-277011 is a potent and selective dopamine D(3) receptor antagonist. SB-277011 attenuates reinforcing propertes of drugs of abuse incluting opiates, cocaine, methamphetamine, nicotine and ethanol. SB-277011A produced a significant decrease in food intake in obese rats. Clinical development of SB-277011A has been halted by GlaxoSmithKline Pharmaceuticals, due to poor bioavailability (~2%) and a very short half-life (<20 min) in primates.
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
