LY-310762

Details

Stereochemistry	ACHIRAL
Molecular Formula	C24H27FN2O2.ClH
Molecular Weight	430.943
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CC1(C)C(=O)N(CCN2CCC(CC2)C(=O)C3=CC=C(F)C=C3)C4=CC=CC=C14

InChI

InChIKey=BOCLFQZPFYNVFD-UHFFFAOYSA-N

InChI=1S/C24H27FN2O2.ClH/c1-24(2)20-5-3-4-6-21(20)27(23(24)29)16-15-26-13-11-18(12-14-26)22(28)17-7-9-19(25)10-8-17;/h3-10,18H,11-16H2,1-2H3;1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C24H27FN2O2
Molecular Weight	394.4818
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Serotonin 1d (5-HT1d) receptor 52 Target ID: CHEMBL2304407 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15189767	Antagonist 2778		249.0 nM [Ki]
5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 1 Target ID: 1.007176E8 Gene Symbol: Htr1b Sources: https://www.ncbi.nlm.nih.gov/pubmed/15189767	Binding Agent 1064

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:58:29 GMT 2023` Edited by `admin` on `Sat Dec 16 18:58:29 GMT 2023`
Record UNII	BUX78WM9U2
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

LY-310762

Code

English

2H-INDOL-2-ONE, 1-(2-(4-(4-FLUOROBENZOYL)-1-PIPERIDINYL)ETHYL)-1,3-DIHYDRO-3,3-DIMETHYL-, MONOHYDROCHLORIDE

Systematic Name

English

LY 310762 HYDROCHLORIDE

Common Name

English

2H-INDOL-2-ONE, 1-(2-(4-(4-FLUOROBENZOYL)-1-PIPERIDINYL)ETHYL)-1,3-DIHYDRO-3,3-DIMETHYL-, HYDROCHLORIDE (1:1)

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID80474689

Created by admin on Sat Dec 16 18:58:29 GMT 2023 , Edited by admin on Sat Dec 16 18:58:29 GMT 2023

PRIMARY

PUBCHEM

11957576

Created by admin on Sat Dec 16 18:58:29 GMT 2023 , Edited by admin on Sat Dec 16 18:58:29 GMT 2023

PRIMARY

FDA UNII

BUX78WM9U2

Created by admin on Sat Dec 16 18:58:29 GMT 2023 , Edited by admin on Sat Dec 16 18:58:29 GMT 2023

PRIMARY

CAS

192927-92-7

Created by admin on Sat Dec 16 18:58:29 GMT 2023 , Edited by admin on Sat Dec 16 18:58:29 GMT 2023

PRIMARY

Related Record Type Details


					ZI18M2JAY5

5-HYDROXYTRYPTAMINE RECEPTOR 1D

TARGET -> INHIBITOR

Interaction Type:

ANTAGONIST

Amount: