Quillaic acid (Quillaja sapogenin) is the major aglycone of the widely studied saponins of the Chilean indigenous tree Quillaja saponaria Mol. Quillaja saponaria bark contains a high percentage of triterpene saponins and has been used for centuries a...
s a cleansing and analgesic agent in Chilean folk medicine. Quillaic acid shows potent antiproliferative activity against different cancer cell lines.
Quillaic acid elicit dose-dependent antinociceptive effects in two murine thermal models. Quillaic acid exhibited strong topical anti-inflammatory activity in different animal models.