Inxight Drugs

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Return Home Inxight Drugs

Home
Browse Drugs
Search
- Structure Search
- Sequence Search
Downloads
About

Show Filters

Hide Filters

Development Status

US Previously Marketed

3

Other

1

Possibly Marketed Outside US

1

All Match

Any Match

Exclude Selected

Exclude Selected

Primary Target

amyloid fibril formation

3

intrinsic apoptotic signaling pathway in response to oxidative stress

3

Pseudomonas aeruginosa growth

1

Staphylococcus aureus growth

1

Vanilloid receptor

1

All Match

Any Match

Exclude Selected

Exclude Selected

Highest Phase

Approved

1

All Match

Any Match

Exclude Selected

Exclude Selected

Approval Year

1921

3

1984

1

Unknown

1

All Match

Any Match

Exclude Selected

Exclude Selected

Condition

Alzheimer’s disease

3

Cancer

3

Non-alcoholic fatty liver disease

3

Vascular dementia

3

Traumatic, acute, chronic, surgical and burn wounds

1

All Match

Any Match

Exclude Selected

Exclude Selected

Treatment Modality

Primary

3

Curative

1

All Match

Any Match

Exclude Selected

Exclude Selected

CNS Activity

CNS Active

4

All Match

Any Match

Exclude Selected

Exclude Selected

Originator

Nipa Laboratories

1

All Match

Any Match

Exclude Selected

Exclude Selected

Substance Class

Chemical

5

All Match

Any Match

Exclude Selected

Exclude Selected

Code System

CAS

5

EPA CompTox

5

FDA UNII

5

PUBCHEM

5

ECHA (EC/EINECS)

4

All Match

Any Match

Exclude Selected

Exclude Selected

Substance Form

Principal Form

3

Salts, Hydrates, Esters, etc.

2

All Match

Any Match

Exclude Selected

Exclude Selected

Showing 1 - 5 of 5 results

First page disabled
Previous page disabled
1
Next page disabled
Next page disabled

ETHYL GALLATE

235I6UDD3L

Export Data
Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

GALLIC ACID

632XD903SP

Export Data
Search for Structure

Status:

US Previously Marketed

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

intrinsic apoptotic signaling pathway in response to oxidative stress

amyloid fibril formation

Conditions:

Vascular dementia

Non-alcoholic fatty liver disease

Alzheimer’s disease

Gallic acid is a polyphenol found in a variety of foods and herbs. Several studies have shown thta gallic acid has neuroprotective and anti-oxidant properties and can be a promising candidate for the treatment of cancer, cardiovascular diseases, neur...

odegenerative disorders, fatty liver disease and many others. Gallic acid acts by protecting cells against oxidative damage caused by reactive species often encountered in biological systems including, hydroxyl, superoxide and peroxyl and the non-radicals, hydrogen peroxide and hypochlorous acid. However, its ability to induce apoptosis, is mainly associated with its prooxidant, rather than antioxidant behavior.

PHENOXYETHANOL

HIE492ZZ3T

Export Data
Search for Structure

Status:

Possibly Marketed Outside US

First approved in 2004

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Vanilloid receptor

Pseudomonas aeruginosa growth

Staphylococcus aureus growth

Conditions:

Traumatic, acute, chronic, surgical and burn wounds

Phenoxyethanol, also known as Ethylene Glycol Monophenyl Ether, is a glycol ether and bactericide (that functions as a disinfectant, antiseptic or antibiotic) that is primarily used as a preservative in cosmetics and beauty products. It is used as a ...

preservative in vaccines. Phenoxyethanol is included in topical antiseptic solutions, like octenisept used for the treatment of traumatic, acute, chronic, surgical and burn wounds, the treatment of bacterial vaginosis, acne lesions and as the mucous membrane antiseptic.

Sodium gallate

9Y9CNL7KUL

Export Data
Search for Structure

Status:

US Previously Marketed

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

intrinsic apoptotic signaling pathway in response to oxidative stress

amyloid fibril formation

Conditions:

Vascular dementia

Non-alcoholic fatty liver disease

Alzheimer’s disease

Gallic acid is a polyphenol found in a variety of foods and herbs. Several studies have shown thta gallic acid has neuroprotective and anti-oxidant properties and can be a promising candidate for the treatment of cancer, cardiovascular diseases, neur...

odegenerative disorders, fatty liver disease and many others. Gallic acid acts by protecting cells against oxidative damage caused by reactive species often encountered in biological systems including, hydroxyl, superoxide and peroxyl and the non-radicals, hydrogen peroxide and hypochlorous acid. However, its ability to induce apoptosis, is mainly associated with its prooxidant, rather than antioxidant behavior.

GALLIC ACID MONOHYDRATE

48339473OT

Export Data
Search for Structure

Status:

US Previously Marketed

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

intrinsic apoptotic signaling pathway in response to oxidative stress

amyloid fibril formation

Conditions:

Vascular dementia

Non-alcoholic fatty liver disease

Alzheimer’s disease

Gallic acid is a polyphenol found in a variety of foods and herbs. Several studies have shown thta gallic acid has neuroprotective and anti-oxidant properties and can be a promising candidate for the treatment of cancer, cardiovascular diseases, neur...

odegenerative disorders, fatty liver disease and many others. Gallic acid acts by protecting cells against oxidative damage caused by reactive species often encountered in biological systems including, hydroxyl, superoxide and peroxyl and the non-radicals, hydrogen peroxide and hypochlorous acid. However, its ability to induce apoptosis, is mainly associated with its prooxidant, rather than antioxidant behavior.

HHS VULNERABILITY DISCLOSURE

For language access assistance, contact the NCATS Public Information Officer

National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966


			version 1.1