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Development Status

US Approved Rx

3

Other

2

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Primary Target

Voltage-sensitive sodium channel

3

Voltage-sensitive sodium channel alpha-subunit

3

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Highest Phase

Approved

3

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Approval Year

1986

3

Unknown

2

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Condition

Head lice infestation

3

Pediculosis

3

Scabies

3

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Treatment Modality

Curative

3

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Originator

Rothamsted Experimental Station

3

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Substance Class

Chemical

4

Mixture

1

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Code System

CAS

5

EPA CompTox

5

FDA UNII

5

PUBCHEM

5

ALANWOOD

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ATC Level 1

ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS

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ATC Level 2

ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS

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ATC Level 3

ECTOPARASITICIDES, INCL. SCABICIDES

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ATC Level 4

Pyrethrines, incl. synthetic compounds

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Substance Form

Salts, Hydrates, Esters, etc.

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Showing 1 - 5 of 5 results

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BIOPERMETHRIN

5O0SBK88B7

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Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

PERMETHRIN

509F88P9SZ

Status:

US Approved Rx (2000)

First approved in 1986

Class:

MIXTURE

Targets:

Voltage-sensitive sodium channel

Voltage-sensitive sodium channel alpha-subunit

Voltage-sensitive sodium channel

Conditions:

Head lice infestation

Permethrin is a synthetic pyrethrin derivative acts as a neurotoxin by depolarizing the nerve cell membrane. Permethrin disrupts the sodium channel current by which membrane repolarization is regulated resulting in fatal paralysis of the nerves in th...

e exoskeletal respiratory muscles of susceptible arthropods, including lice and mite. Permethrin is sold under brand names NIx and Elimite to treat pediculosis, scabies and demodicidosis.

PERMETHRIN, CIS-(+)-

620Q217008

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Status:

US Approved Rx (2000)

First approved in 1986

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Voltage-sensitive sodium channel

Voltage-sensitive sodium channel alpha-subunit

Voltage-sensitive sodium channel

Conditions:

Head lice infestation

Permethrin is a synthetic pyrethrin derivative acts as a neurotoxin by depolarizing the nerve cell membrane. Permethrin disrupts the sodium channel current by which membrane repolarization is regulated resulting in fatal paralysis of the nerves in th...

e exoskeletal respiratory muscles of susceptible arthropods, including lice and mite. Permethrin is sold under brand names NIx and Elimite to treat pediculosis, scabies and demodicidosis.

PERMETHRIN, CIS-

GC30YV53C8

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Status:

US Approved Rx (2000)

First approved in 1986

Class (Stereo):

CHEMICAL (RACEMIC)

Targets:

Voltage-sensitive sodium channel

Voltage-sensitive sodium channel alpha-subunit

Voltage-sensitive sodium channel

Conditions:

Head lice infestation

Permethrin is a synthetic pyrethrin derivative acts as a neurotoxin by depolarizing the nerve cell membrane. Permethrin disrupts the sodium channel current by which membrane repolarization is regulated resulting in fatal paralysis of the nerves in th...

e exoskeletal respiratory muscles of susceptible arthropods, including lice and mite. Permethrin is sold under brand names NIx and Elimite to treat pediculosis, scabies and demodicidosis.

TRANSPERMETHRIN

MQP2PAM1G5

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Status:

Other

Class (Stereo):

CHEMICAL (RACEMIC)

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