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Development Status

Other

4

Possibly Marketed Outside US

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Primary Target

Anandamide amidohydrolase

1

Leukocyte elastase

1

Leukocyte proteinase 3

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Approval Year

Unknown

4

2018

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Condition

Unknown

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Originator

Steinkopf, W.|Buchheim, K.|Beythien, K.|Dudek, H.|Eisold, J.|Gall, J.|Jaeger, P.|Reumuth, H.t|Semenoff, A.s|Wemme, A.

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Substance Class

Chemical

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Code System

CAS

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EPA CompTox

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FDA UNII

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PUBCHEM

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ECHA (EC/EINECS)

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Substance Form

Principal Form

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Salts, Hydrates, Esters, etc.

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Showing 1 - 5 of 5 results

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2-AMINO-3-NITROPHENOL

A7F97ZPU2W

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

3-(CHLOROMETHYL)PYRIDINE

8QM5JL9CFT

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

PHENYLMETHANESULFONYL FLUORIDE

57KD15003I

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Leukocyte elastase

Leukocyte proteinase 3

Anandamide amidohydrolase

Anandamide amidohydrolase

Conditions:

Phenylmethanesulfonyl fluoride is an irreversible inhibitor of serine proteases commonly used in the preparation of cell lysates. Phenylmethanesulfonyl fluoride has been used as a supplement in nuclear protein extraction and inhibitor of cholesterol ...

esterase (CE) and pseudocholinesterase (PCE). Administration of PMSF produces analgesia unrelated to its anticholinesterase effect and prolongs the analgesic effect of centrally administered β-endorphin. The physiological and toxicological properties of this compound have not been evaluated in humans.

4-HYDROXYBENZYL ALCOHOL

1A3AH1FP1B

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Status:

Possibly Marketed Outside US

First approved in 2018

Class (Stereo):

CHEMICAL (ACHIRAL)

3-CHLOROMETHYLPYRIDINE HYDROCHLORIDE

BQA8FYP4YN

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

HHS VULNERABILITY DISCLOSURE

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