Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H8O2 |
| Molecular Weight | 124.1372 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OCC1=CC=C(O)C=C1
InChI
InChIKey=BVJSUAQZOZWCKN-UHFFFAOYSA-N
InChI=1S/C7H8O2/c8-5-6-1-3-7(9)4-2-6/h1-4,8-9H,5H2
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| p-Hydroxybenzyl alcohol attenuates learning deficits in the inhibitory avoidance task: involvement of serotonergic and dopaminergic systems. | 1996 |
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| Effects of Gastrodia elata and its active constituents on scopolamine-induced amnesia in rats. | 1996 Aug |
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| Gastrodin and p-hydroxybenzyl alcohol facilitate memory consolidation and retrieval, but not acquisition, on the passive avoidance task in rats. | 1997 Mar |
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| Substituent effects on carbocation stability: the pK(R) for p-quinone methide. | 2003 Jul 23 |
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| 4-Hydroxybenzyl alcohol accumulates in flowers and developing fruits of carrot and inhibits seed formation. | 2003 Jun |
|
| [Chemical constituents from the rhizoma of Arundina graminifolia]. | 2004 Feb |
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| Chemical constituents of the rhizomes of Coeloglossum viride var. bracteatum. | 2004 Mar |
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| Metabolism of gallic acid and catechin by Lactobacillus hilgardii from wine. | 2004 Oct 20 |
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| Bioactivation of 4-methylphenol (p-cresol) via cytochrome P450-mediated aromatic oxidation in human liver microsomes. | 2005 Dec |
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| New phenolic glycosides from the seeds of Cucurbita moschata. | 2005 Feb |
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| Gastrodia elata blume and an active component, p-hydroxybenzyl alcohol reduce focal ischemic brain injury through antioxidant related gene expressions. | 2005 Jun |
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| In vitro metabolism of nitric oxide-donating aspirin: the effect of positional isomerism. | 2005 Mar |
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| Colorimetric evaluation of phenolic content and GC-MS characterization of phenolic composition of alimentary and cosmetic argan oil and press cake. | 2005 Nov 16 |
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| A new citryl glycoside from Gastrodia elata and its inhibitory activity on GABA transaminase. | 2006 Dec |
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| Chemical fingerprint analysis of rhizomes of Gymnadenia conopsea by HPLC-DAD-MSn. | 2006 Dec 5 |
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| Anxiolytic-like effects of Gastrodia elata and its phenolic constituents in mice. | 2006 Feb |
|
| [The production of gastrodin through biotransformation of p-hydroxybenzaldehyde by cell suspension culture of Datura stramonium]. | 2006 Oct |
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| Anti-inflammatory action of phenolic compounds from Gastrodia elata root. | 2006 Oct |
|
| [Production of gastrodin through biotransformation of p-hydroxybenzaldehyde by cell suspension cultures of Datura tatula L]. | 2006 Sep |
|
| [Evaluation of the quality of Gastrodia elata Bl. by HPLC-DAD/MS]. | 2007 Apr |
|
| Phenolic constituents from the rhizomes of Gastrodia elata. | 2007 Feb |
|
| Development and validation of an RP-HPLC method for quantitative determination of vanillin and related phenolic compounds in Vanilla planifolia. | 2007 Jan |
|
| Inhibitory effect of p-hydroxybenzyl alcohol on tyrosinase activity and melanogenesis. | 2007 Jun |
|
| Host plant-dependent metabolism of 4-hydroxybenzylglucosinolate in Pieris rapae: substrate specificity and effects of genetic modification and plant nitrile hydratase. | 2007 Nov |
|
| Vanillin, 4-hydroxybenzyl aldehyde and 4-hydroxybenzyl alcohol prevent hippocampal CA1 cell death following global ischemia. | 2007 Nov 21 |
|
| [Studies on chemical constituents from root of Cynanchum atratum]. | 2007 Sep |
|
| Anti-angiogenic, anti-inflammatory and anti-nociceptive activity of 4-hydroxybenzyl alcohol. | 2007 Sep |
|
| Studies on the antioxidant activities of natural vanilla extract and its constituent compounds through in vitro models. | 2007 Sep 19 |
|
| Biotransformation and pharmacokinetics of 4-(3,4-dihydroxybenzoyloxymethyl)phenyl-O-beta-D-glucopyranoside, an antioxidant isolated from Origanum vulgare. | 2008 Apr 23 |
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| Bazedoxifene for the prevention of postmenopausal osteoporosis. | 2008 Dec |
|
| Effect of borneol on the distribution of gastrodin to the brain in mice via oral administration. | 2008 Feb |
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| Distribution and metabolism of gastrodin in rat brain. | 2008 Jan 22 |
|
| The photo-Favorskii reaction of p-hydroxyphenacyl compounds is initiated by water-assisted, adiabatic extrusion of a triplet biradical. | 2008 Mar 19 |
|
| [Brain targeting of gastrodin nasal in situ gel]. | 2008 May |
|
| Engineering and Applications of fungal laccases for organic synthesis. | 2008 Nov 20 |
|
| Pharmacokinetics of gastrodin and its metabolite p-hydroxybenzyl alcohol in rat blood, brain and bile by microdialysis coupled to LC-MS/MS. | 2008 Nov 4 |
|
| Determination and pharmacokinetics of gastrodin and p-hydroxybenzylalcohol after oral administration of Gastrodia elata Bl. extract in rats by high-performance liquid chromatography-electrospray ionization mass spectrometric method. | 2008 Oct |
|
| Microfluidic synthesis and catalytic application of PVP-stabilized, approximately 1 nm gold clusters. | 2008 Oct 21 |
|
| Metabolites from endophytic fungus S20 of Cephalotaxus hainanensis. | 2009 Aug |
|
| The hunt for natural skin whitening agents. | 2009 Dec 10 |
|
| A cascade biodegradable polymer based on alternating cyclization and elimination reactions. | 2009 Dec 30 |
|
| A fragile metabolic network adapted for cooperation in the symbiotic bacterium Buchnera aphidicola. | 2009 Feb 21 |
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| Experimental stroke protection induced by 4-hydroxybenzyl alcohol is cancelled by bacitracin. | 2009 Jun |
|
| [Simultaneous determination of four components in Gastrodia elata by RP-HPLC]. | 2009 Nov |
|
| Biosynthesis of vanillin via ferulic acid in Vanilla planifolia. | 2009 Nov 11 |
|
| Formaldehyde in the indoor environment. | 2010 Apr 14 |
|
| Structure-toxicity relationship of phenolic analogs as anti-melanoma agents: an enzyme directed prodrug approach. | 2010 Feb 12 |
|
| Neuroprotective effect of 4-hydroxybenzyl alcohol against transient focal cerebral ischemia via anti-apoptosis in rats. | 2010 Jan 13 |
|
| Supercritical fluid chromatography of myrosinase reaction products in ground yellow mustard seed oil. | 2010 May |
|
| Genetic transformation of lignin degrading fungi facilitated by Agrobacterium tumefaciens. | 2010 Sep 14 |
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JECFA EVALUATION |
4-HYDROXYBENZYL ALCOHOL
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888
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1A3AH1FP1B
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67410
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125
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DTXSID8073920
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C018966
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210-768-0
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227926
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GASTRODIGENIN
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2045942
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623-05-2
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SUBSTANCE RECORD
