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Details

Stereochemistry ACHIRAL
Molecular Formula C7H8O2
Molecular Weight 124.1372
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 4-HYDROXYBENZYL ALCOHOL

SMILES

OCC1=CC=C(O)C=C1

InChI

InChIKey=BVJSUAQZOZWCKN-UHFFFAOYSA-N
InChI=1S/C7H8O2/c8-5-6-1-3-7(9)4-2-6/h1-4,8-9H,5H2

HIDE SMILES / InChI

Molecular Formula C7H8O2
Molecular Weight 124.1372
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
[Constituents of Gymnadenia conopsea].
2010-11
Genetic transformation of lignin degrading fungi facilitated by Agrobacterium tumefaciens.
2010-09-14
Supercritical fluid chromatography of myrosinase reaction products in ground yellow mustard seed oil.
2010-05
Formaldehyde in the indoor environment.
2010-04-14
Structure-toxicity relationship of phenolic analogs as anti-melanoma agents: an enzyme directed prodrug approach.
2010-02-12
Secondary metabolites of the phytopathogen Peronophythora litchii.
2010-02
Neuroprotective effect of 4-hydroxybenzyl alcohol against transient focal cerebral ischemia via anti-apoptosis in rats.
2010-01-13
A cascade biodegradable polymer based on alternating cyclization and elimination reactions.
2009-12-30
The hunt for natural skin whitening agents.
2009-12-10
Biosynthesis of vanillin via ferulic acid in Vanilla planifolia.
2009-11-11
[Simultaneous determination of four components in Gastrodia elata by RP-HPLC].
2009-11
Metabolites from endophytic fungus S20 of Cephalotaxus hainanensis.
2009-08
4-(Hydroxy-meth-yl)phenol.
2009-06-27
Experimental stroke protection induced by 4-hydroxybenzyl alcohol is cancelled by bacitracin.
2009-06
A fragile metabolic network adapted for cooperation in the symbiotic bacterium Buchnera aphidicola.
2009-02-21
Bazedoxifene for the prevention of postmenopausal osteoporosis.
2008-12
Engineering and Applications of fungal laccases for organic synthesis.
2008-11-20
Pharmacokinetics of gastrodin and its metabolite p-hydroxybenzyl alcohol in rat blood, brain and bile by microdialysis coupled to LC-MS/MS.
2008-11-04
Microfluidic synthesis and catalytic application of PVP-stabilized, approximately 1 nm gold clusters.
2008-10-21
Determination and pharmacokinetics of gastrodin and p-hydroxybenzylalcohol after oral administration of Gastrodia elata Bl. extract in rats by high-performance liquid chromatography-electrospray ionization mass spectrometric method.
2008-10
[Brain targeting of gastrodin nasal in situ gel].
2008-05
Biotransformation and pharmacokinetics of 4-(3,4-dihydroxybenzoyloxymethyl)phenyl-O-beta-D-glucopyranoside, an antioxidant isolated from Origanum vulgare.
2008-04-23
The photo-Favorskii reaction of p-hydroxyphenacyl compounds is initiated by water-assisted, adiabatic extrusion of a triplet biradical.
2008-03-19
Effect of borneol on the distribution of gastrodin to the brain in mice via oral administration.
2008-02
Distribution and metabolism of gastrodin in rat brain.
2008-01-22
Vanillin, 4-hydroxybenzyl aldehyde and 4-hydroxybenzyl alcohol prevent hippocampal CA1 cell death following global ischemia.
2007-11-21
Host plant-dependent metabolism of 4-hydroxybenzylglucosinolate in Pieris rapae: substrate specificity and effects of genetic modification and plant nitrile hydratase.
2007-11
Studies on the antioxidant activities of natural vanilla extract and its constituent compounds through in vitro models.
2007-09-19
[Studies on chemical constituents from root of Cynanchum atratum].
2007-09
Anti-angiogenic, anti-inflammatory and anti-nociceptive activity of 4-hydroxybenzyl alcohol.
2007-09
Inhibitory effect of p-hydroxybenzyl alcohol on tyrosinase activity and melanogenesis.
2007-06
[Evaluation of the quality of Gastrodia elata Bl. by HPLC-DAD/MS].
2007-04
Phenolic constituents from the rhizomes of Gastrodia elata.
2007-02
Development and validation of an RP-HPLC method for quantitative determination of vanillin and related phenolic compounds in Vanilla planifolia.
2007-01
Chemical fingerprint analysis of rhizomes of Gymnadenia conopsea by HPLC-DAD-MSn.
2006-12-05
A new citryl glycoside from Gastrodia elata and its inhibitory activity on GABA transaminase.
2006-12
[The production of gastrodin through biotransformation of p-hydroxybenzaldehyde by cell suspension culture of Datura stramonium].
2006-10
Anti-inflammatory action of phenolic compounds from Gastrodia elata root.
2006-10
[Production of gastrodin through biotransformation of p-hydroxybenzaldehyde by cell suspension cultures of Datura tatula L].
2006-09
Anxiolytic-like effects of Gastrodia elata and its phenolic constituents in mice.
2006-02
Bioactivation of 4-methylphenol (p-cresol) via cytochrome P450-mediated aromatic oxidation in human liver microsomes.
2005-12
Colorimetric evaluation of phenolic content and GC-MS characterization of phenolic composition of alimentary and cosmetic argan oil and press cake.
2005-11-16
Gastrodia elata blume and an active component, p-hydroxybenzyl alcohol reduce focal ischemic brain injury through antioxidant related gene expressions.
2005-06
In vitro metabolism of nitric oxide-donating aspirin: the effect of positional isomerism.
2005-03
New phenolic glycosides from the seeds of Cucurbita moschata.
2005-02
Metabolism of gallic acid and catechin by Lactobacillus hilgardii from wine.
2004-10-20
[Chemical constituents from the rhizoma of Arundina graminifolia].
2004-02
Gastrodin and p-hydroxybenzyl alcohol facilitate memory consolidation and retrieval, but not acquisition, on the passive avoidance task in rats.
1997-03
Effects of Gastrodia elata and its active constituents on scopolamine-induced amnesia in rats.
1996-08
p-Hydroxybenzyl alcohol attenuates learning deficits in the inhibitory avoidance task: involvement of serotonergic and dopaminergic systems.
1996
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:18:45 GMT 2025
Edited
by admin
on Mon Mar 31 19:18:45 GMT 2025
Record UNII
1A3AH1FP1B
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HYDROXYBENZYL ALCOHOL
INCI  
INCI  
Preferred Name English
4-HYDROXYBENZYL ALCOHOL
FHFI  
Systematic Name English
(4-HYDROXYPHENYL)METHANOL
Systematic Name English
4-HYDROXYBENZYL ALCOHOL [FHFI]
Common Name English
NSC-227926
Code English
BENZENEMETHANOL, 4-HYDROXY-
Systematic Name English
.ALPHA.-HYDROXY-P-CRESOL
Common Name English
GASTRODIGENIN
Brand Name English
4-(HYDROXYMETHYL)PHENOL
Systematic Name English
4-METHYLOLPHENOL
Systematic Name English
FEMA NO. 3987
Code English
4-HYDROXYBENZENEMETHANOL
Systematic Name English
Classification Tree Code System Code
JECFA EVALUATION 4-HYDROXYBENZYL ALCOHOL
Created by admin on Mon Mar 31 19:18:45 GMT 2025 , Edited by admin on Mon Mar 31 19:18:45 GMT 2025
Code System Code Type Description
JECFA MONOGRAPH
888
Created by admin on Mon Mar 31 19:18:45 GMT 2025 , Edited by admin on Mon Mar 31 19:18:45 GMT 2025
PRIMARY
FDA UNII
1A3AH1FP1B
Created by admin on Mon Mar 31 19:18:45 GMT 2025 , Edited by admin on Mon Mar 31 19:18:45 GMT 2025
PRIMARY
DAILYMED
1A3AH1FP1B
Created by admin on Mon Mar 31 19:18:45 GMT 2025 , Edited by admin on Mon Mar 31 19:18:45 GMT 2025
PRIMARY
CHEBI
67410
Created by admin on Mon Mar 31 19:18:45 GMT 2025 , Edited by admin on Mon Mar 31 19:18:45 GMT 2025
PRIMARY
PUBCHEM
125
Created by admin on Mon Mar 31 19:18:45 GMT 2025 , Edited by admin on Mon Mar 31 19:18:45 GMT 2025
PRIMARY
EPA CompTox
DTXSID8073920
Created by admin on Mon Mar 31 19:18:45 GMT 2025 , Edited by admin on Mon Mar 31 19:18:45 GMT 2025
PRIMARY
MESH
C018966
Created by admin on Mon Mar 31 19:18:45 GMT 2025 , Edited by admin on Mon Mar 31 19:18:45 GMT 2025
PRIMARY
ECHA (EC/EINECS)
210-768-0
Created by admin on Mon Mar 31 19:18:45 GMT 2025 , Edited by admin on Mon Mar 31 19:18:45 GMT 2025
PRIMARY
NSC
227926
Created by admin on Mon Mar 31 19:18:45 GMT 2025 , Edited by admin on Mon Mar 31 19:18:45 GMT 2025
PRIMARY
WIKIPEDIA
GASTRODIGENIN
Created by admin on Mon Mar 31 19:18:45 GMT 2025 , Edited by admin on Mon Mar 31 19:18:45 GMT 2025
PRIMARY
RXCUI
2045942
Created by admin on Mon Mar 31 19:18:45 GMT 2025 , Edited by admin on Mon Mar 31 19:18:45 GMT 2025
PRIMARY
CAS
623-05-2
Created by admin on Mon Mar 31 19:18:45 GMT 2025 , Edited by admin on Mon Mar 31 19:18:45 GMT 2025
PRIMARY