U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Status:
Investigational
Source:
NCT00345618: Phase 3 Interventional Completed Embolism
(2006)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Idrabiotaparinux, a biotinylated idraparinux, was developed by Sanofi as a long-acting inhibitor of factor Xa. Idrabiotaparinux participated in clinical trials phase III to prevent stroke and systemic thromboembolic events in patients with atrial fibrillation. The study was prematurely terminated, because of unknown reason. In addition, the drug was involved in phase II for patients with pulmonary embolism. Sanofi has discontinued development of idrabiotaparinux.
Status:
Investigational
Source:
NCT00285025: Phase 2 Interventional Completed Alzheimer Disease
(2005)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Paliroden is an orally active drug that activates the synthesis of endogenous neurotrophins or nerve growth factors. Paliroden was investigated in phase II clinical trial in patients with Alzheimer's disease and to evaluate its effect on 18F-Dopa PET imaging in patients with Parkinson's disease. The further development of paliroden was discontinued due to its insufficient efficacy.
Status:
Investigational
Source:
NCT00285025: Phase 2 Interventional Completed Alzheimer Disease
(2005)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Paliroden is an orally active drug that activates the synthesis of endogenous neurotrophins or nerve growth factors. Paliroden was investigated in phase II clinical trial in patients with Alzheimer's disease and to evaluate its effect on 18F-Dopa PET imaging in patients with Parkinson's disease. The further development of paliroden was discontinued due to its insufficient efficacy.
Status:
Investigational
Source:
NCT00345618: Phase 3 Interventional Completed Embolism
(2006)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Idrabiotaparinux, a biotinylated idraparinux, was developed by Sanofi as a long-acting inhibitor of factor Xa. Idrabiotaparinux participated in clinical trials phase III to prevent stroke and systemic thromboembolic events in patients with atrial fibrillation. The study was prematurely terminated, because of unknown reason. In addition, the drug was involved in phase II for patients with pulmonary embolism. Sanofi has discontinued development of idrabiotaparinux.