| Stereochemistry | ACHIRAL |
| Molecular Formula | C26H24F3N |
| Molecular Weight | 407.4707 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
FC(F)(F)C1=CC(=CC=C1)C2=CCN(CCC3=CC=C(C=C3)C4=CC=CC=C4)CC2
InChI
InChIKey=CNEWKIDCGDXBDE-UHFFFAOYSA-N
InChI=1S/C26H24F3N/c27-26(28,29)25-8-4-7-24(19-25)23-14-17-30(18-15-23)16-13-20-9-11-22(12-10-20)21-5-2-1-3-6-21/h1-12,14,19H,13,15-18H2
Paliroden is an orally active drug that activates the synthesis of endogenous neurotrophins or nerve growth factors. Paliroden was investigated in phase II clinical trial in patients with Alzheimer's disease and to evaluate its effect on 18F-Dopa PET imaging in patients with Parkinson's disease. The further development of paliroden was discontinued due to its insufficient efficacy.
Originator
Approval Year
PubMed
ACTIVE MOIETY
SALT/SOLVATE (PARENT)
