Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C26H24F3N |
| Molecular Weight | 407.4707 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
FC(F)(F)C1=CC(=CC=C1)C2=CCN(CCC3=CC=C(C=C3)C4=CC=CC=C4)CC2
InChI
InChIKey=CNEWKIDCGDXBDE-UHFFFAOYSA-N
InChI=1S/C26H24F3N/c27-26(28,29)25-8-4-7-24(19-25)23-14-17-30(18-15-23)16-13-20-9-11-22(12-10-20)21-5-2-1-3-6-21/h1-12,14,19H,13,15-18H2
Paliroden is an orally active drug that activates the synthesis of endogenous neurotrophins or nerve growth factors. Paliroden was investigated in phase II clinical trial in patients with Alzheimer's disease and to evaluate its effect on 18F-Dopa PET imaging in patients with Parkinson's disease. The further development of paliroden was discontinued due to its insufficient efficacy.
Originator
Approval Year
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Official Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Code | English | ||
|
Systematic Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
NCI_THESAURUS |
C1509
Created by
admin on Mon Mar 31 18:30:35 GMT 2025 , Edited by admin on Mon Mar 31 18:30:35 GMT 2025
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
CHEMBL2107767
Created by
admin on Mon Mar 31 18:30:35 GMT 2025 , Edited by admin on Mon Mar 31 18:30:35 GMT 2025
|
PRIMARY | |||
|
DB05454
Created by
admin on Mon Mar 31 18:30:36 GMT 2025 , Edited by admin on Mon Mar 31 18:30:36 GMT 2025
|
PRIMARY | |||
|
300000034324
Created by
admin on Mon Mar 31 18:30:36 GMT 2025 , Edited by admin on Mon Mar 31 18:30:36 GMT 2025
|
PRIMARY | |||
|
8638
Created by
admin on Mon Mar 31 18:30:35 GMT 2025 , Edited by admin on Mon Mar 31 18:30:35 GMT 2025
|
PRIMARY | |||
|
17VJ76L90T
Created by
admin on Mon Mar 31 18:30:36 GMT 2025 , Edited by admin on Mon Mar 31 18:30:36 GMT 2025
|
PRIMARY | |||
|
188396-77-2
Created by
admin on Mon Mar 31 18:30:35 GMT 2025 , Edited by admin on Mon Mar 31 18:30:35 GMT 2025
|
PRIMARY | |||
|
11567682
Created by
admin on Mon Mar 31 18:30:35 GMT 2025 , Edited by admin on Mon Mar 31 18:30:35 GMT 2025
|
PRIMARY | |||
|
C82298
Created by
admin on Mon Mar 31 18:30:35 GMT 2025 , Edited by admin on Mon Mar 31 18:30:35 GMT 2025
|
PRIMARY | |||
|
DTXSID60870180
Created by
admin on Mon Mar 31 18:30:36 GMT 2025 , Edited by admin on Mon Mar 31 18:30:36 GMT 2025
|
PRIMARY |
ACTIVE MOIETY
SALT/SOLVATE (PARENT)
