U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Antrafenine (SL 73033 or 2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl 2-[[7-(trifluoromethyl)-4-quinolinyl]amino]benzoate) showed marked analgesic activity, long duration of action, and excellent tolerance in pharmacological and toxicological studies. Antrafenine exerts anti-inflammatory effects. It has been studied in the treatment of osteoarthritis.