Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C30H26F6N4O2 |
| Molecular Weight | 588.5435 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
FC(F)(F)C1=CC2=C(C=C1)C(NC3=C(C=CC=C3)C(=O)OCCN4CCN(CC4)C5=CC(=CC=C5)C(F)(F)F)=CC=N2
InChI
InChIKey=NWGGKKGAFZIVBJ-UHFFFAOYSA-N
InChI=1S/C30H26F6N4O2/c31-29(32,33)20-4-3-5-22(18-20)40-14-12-39(13-15-40)16-17-42-28(41)24-6-1-2-7-25(24)38-26-10-11-37-27-19-21(30(34,35)36)8-9-23(26)27/h1-11,18-19H,12-17H2,(H,37,38)
| Molecular Formula | C30H26F6N4O2 |
| Molecular Weight | 588.5435 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Antrafenine (SL 73033 or 2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl 2-[[7-(trifluoromethyl)-4-quinolinyl]amino]benzoate) showed marked analgesic activity, long duration of action, and excellent tolerance in pharmacological and toxicological studies. Antrafenine exerts anti-inflammatory effects. It has been studied in the treatment of osteoarthritis.
Originator
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:28:58 GMT 2023
by
admin
on
Fri Dec 15 15:28:58 GMT 2023
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| Record UNII |
21FS93Y6OE
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| Record Status |
Validated (UNII)
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| Record Version |
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C245
Created by
admin on Fri Dec 15 15:28:58 GMT 2023 , Edited by admin on Fri Dec 15 15:28:58 GMT 2023
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| Code System | Code | Type | Description | ||
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3939
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DTXSID60203833
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68723
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CHEMBL345524
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C017014
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m52
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admin on Fri Dec 15 15:28:58 GMT 2023 , Edited by admin on Fri Dec 15 15:28:58 GMT 2023
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PRIMARY | Merck Index | ||
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ANTRAFENINE
Created by
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55300-29-3
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3677
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DB01419
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C72107
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SUB05530MIG
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100000086973
Created by
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21FS93Y6OE
Created by
admin on Fri Dec 15 15:28:58 GMT 2023 , Edited by admin on Fri Dec 15 15:28:58 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |
