U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Showing 1 - 10 of 12 results

Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)

Tiazuril is a triazinedione derivative patented by American multinational pharmaceutical corporation Pfizer Inc. as the coccidiostatic agent. Tiazuril controlled all the major species of poultry coccidia at low concentrations but elicited toxicologic...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)

Terlakiren (also known as CP80794) is a cysteinamide derivative patented by Pfizer Inc. as potent renin inhibitor. Terlakirens inhibitory potency against plasma renin of guinea pigs, dogs, and monkeys ranges from 0.3 to 0.7 nM. In preclinical models...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)

FLUMIZOLE, a substituted diarylimidazole, is a weak acidic, nonsteroidal, anti-inflammatory agent. It is a potent cyclooxygenase inhibitor. FLUMIZOLE is severalfold more potent than indomethacin and 470 times more active than phenylbutazone in a syst...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)

Propikacin (also known as UK31214) is kanamycin B derivative patented by Pfizer Inc. as antibacterial compound. In preclinical studies Propikacin shows antibacterial activity against the Enterobacteriaceae, P. stuartii strains and the gentamicin-resi...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)


Sulopenem is a thiolanylthiopenem derivative patented by American multinational pharmaceutical corporation Pfizer Inc as an antibiotic with broad-spectrum antibacterial activity against most gram-positive and gram-negative bacteria. Sulopenem showed ...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)

Sudoxicam is a nonsteroidal anti-inflammatory drug patented by American multinational pharmaceutical corporation Pfizer for the treatment of thrombosis. Sudoxicam strongly inhibited aggregation of rabbit, dog, and human platelets caused by collagen, ...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)

Tibric Acid is a sulfamoylbenzoic acid derivative patented by American multinational pharmaceutical corporation Pfizer Inc. as a hypolipidemic agent. In preclinical models, Tibric acid, given orally, was more effective than clofibrate in preventing t...
Status:
US Previously Marketed
First approved in 1955

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

HYDROXYDIONE is a neuroactive steroid used formerly as a general anesthetic. It was discontinued due to a high incidence of post-anesthetic thrombophlebitis, delayed onset of anesthesia and an unacceptably long duration of action.
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)


Sulopenem is a thiolanylthiopenem derivative patented by American multinational pharmaceutical corporation Pfizer Inc as an antibiotic with broad-spectrum antibacterial activity against most gram-positive and gram-negative bacteria. Sulopenem showed ...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)


Sulopenem is a thiolanylthiopenem derivative patented by American multinational pharmaceutical corporation Pfizer Inc as an antibiotic with broad-spectrum antibacterial activity against most gram-positive and gram-negative bacteria. Sulopenem showed ...

Showing 1 - 10 of 12 results