U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Declopramide is an apoptosis inducer. Also, it inhibits NFkappaB activation by inhibition of IkappaBbeta breakdown. In preclinical research, Declopramide demonstrated strong antitumor properties. It had been in phase II clinical trials for the treatment of colorectal cancer. However, this research has been discontinued.
Status:
Possibly Marketed Outside US
Source:
SpaGelpatch 42degrees celsius CORSET by SENNY STUDIO Co., Ltd
(2017)
Source URL:
First approved in 2017
Source:
SpaGelpatch 42degrees celsius CORSET by SENNY STUDIO Co., Ltd
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Cordycepin, or 3'-deoxyadenosine, is a derivative of the nucleoside adenosine, differing from the latter by the absence of the hydroxy group in the 3' position of its ribose part. Cytostatic effect of cordycepin is due to incorporation of phospho-cordycepin into mRNA and inhibition of mRNA synthesis. Cordycepin exhibit rapid antidepressant effect due to potentiation of AMPA receptors
Declopramide is an apoptosis inducer. Also, it inhibits NFkappaB activation by inhibition of IkappaBbeta breakdown. In preclinical research, Declopramide demonstrated strong antitumor properties. It had been in phase II clinical trials for the treatment of colorectal cancer. However, this research has been discontinued.