Stereochemistry | ABSOLUTE |
Molecular Formula | C10H13N5O3 |
Molecular Weight | 251.2419 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 3 / 3 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=NC=NC2=C1N=CN2[C@@H]3O[C@H](CO)C[C@H]3O
InChI
InChIKey=OFEZSBMBBKLLBJ-BAJZRUMYSA-N
InChI=1S/C10H13N5O3/c11-8-7-9(13-3-12-8)15(4-14-7)10-6(17)1-5(2-16)18-10/h3-6,10,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,10+/m0/s1
Cordycepin, or 3'-deoxyadenosine, is a derivative of the nucleoside adenosine, differing from the latter by the absence of the hydroxy group in the 3' position of its ribose part. Cytostatic effect of cordycepin is due to incorporation of phospho-cordycepin into mRNA and inhibition of mRNA synthesis. Cordycepin exhibit rapid antidepressant effect due to potentiation of AMPA receptors
CNS Activity
Originator
Approval Year
Sourcing
PubMed
Sample Use Guides
Cordycepin is administred via IV infusions at escalating doses starting from 6mg/m2
Route of Administration:
Intravenous