Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Micafungin (trade name Mycamine) is an echinocandin antifungal drug. Micafungin, the active ingredient in Mycamine, inhibits the synthesis of 1,3-β-D-glucan, an essential component of fungal cell walls, which is not present in mammalian cells. Micafu...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Cefdinir is an extended-spectrum, semisynthetic cephalosporin, for oral administration. As with other cephalosporins, bactericidal activity of cefdinir results from inhibition of cell wall synthesis. Cefdinir is stable in the presence of some, but no...
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Fosmidomycin (3-(formylhydroxyamino)-propylphosphonic acid mono-sodium salt, 3-(N-formyl-N-hydroxyamino)-propylphosphonic acid mono-sodium salt, FR-31564) is a potent inhibitor of P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (PfDXR),...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Kifunensine is an immunoactive compound originally produced by Kitasatosporia kifunense, which displays competitive inhibition against immunosuppressive factor in tumor-bearing mice. Kifunensine has also been shown to be a potent inhibitor of the pur...
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
FK-960 [N-(4-acetyl-1-piperazinyl)-p-fluorobenzamide monohydrate], a novel putative anti-dementia drug of piperazine derivative, ameliorates memory deficits in a variety of animal models of dementia in rats and monkeys, and also augments long-term po...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Zenarestat (FK-366; FR-74366) is an aldose reductase (AR) inhibitor investigated as a treatment for diabetic neuropathy and cataract. Zenarestat is a highly specific AR inhibitor, it did not affect the activities of enzymes in the glycolysis pathway...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Zotepine is a potent antipsychotic and antidepressive drug, which was developed in Japan and used in many countries for the treatment of schizophrenia. Zotepine has high affinity to D2, 5-HT2A, 5-HT2C, 5-HT6, 5-HT7, alpha1A, H1, and D1 receptors at t...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Cefoselis sulphate is a new parenteral cephalosporin, which was launched into therapy in Japan on 9 September, 1998, under the brand name Wincef. Cefoselis sulphate, like all the other beta-lactams, exhibits its bactericidal eff ects by binding to pe...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
(R)-FK480 is enantiomer of a cholecystokin-type-A (CCK-A) receptor antagonist FK480. Binding of (R)-FK480 to CCK-A is 26 times less potent than (S)-FK480.
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Piroheptine is an antagonist of muscarinic acetylcholine receptors. The drug was used for the treatment of Parkinson's disease, however, it is no longer marketed.