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Originator

Fosbinder, R.J.|Walter, L.A.

9

Pfizer

420

Eli Lilly

237

Merck

216

GlaxoSmithKline

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Development Status

US Previously Marketed

7

Possibly Marketed Outside US

2

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Primary Target

Bacterial dihydropteroate synthase

9

Escherichia coli

7

folic acid biosynthetic process

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Highest Phase

Approved

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Approval Year

1940

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Unknown

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Condition

Vaginal infections

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Bacterial eye infections

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Treatment Modality

Curative

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CNS Activity

CNS Penetrant

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Substance Class

Chemical

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CAS

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FDA UNII

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PUBCHEM

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EPA CompTox

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MERCK INDEX

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ATC Level 1

ALIMENTARY TRACT AND METABOLISM

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ANTIINFECTIVES FOR SYSTEMIC USE

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DERMATOLOGICALS

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ATC Level 2

ANTIBACTERIALS FOR SYSTEMIC USE

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ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE

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ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS

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ATC Level 3

CHEMOTHERAPEUTICS FOR TOPICAL USE

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INTESTINAL ANTIINFECTIVES

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SULFONAMIDES AND TRIMETHOPRIM

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ATC Level 4

Sulfonamides

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Short-acting sulfonamides

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Substance Form

Salts, Hydrates, Esters, etc.

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Principal Form

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Showing 1 - 9 of 9 results

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SULFATHIAZOLE

Y7FKS2XWQH

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Status:

US Previously Marketed

First approved in 1940

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Escherichia coli

folic acid biosynthetic process

Bacterial dihydropteroate synthase

Escherichia coli

Conditions:

Vaginal infections

Sulfathiazole is a short-acting sulfonamide with properties similar to those of sulfamethoxazole. It is now rarely used systemically due to its toxicity. Sulfathiazole is used with other sulfonamides, usually sulfabenzamide and sulfacetamide, in prep...

arations for the topical treatment of vaginal infections and is also used with other drugs in the treatment of skin infections. Sulfathiazole sodium has been applied topically with other drugs in the treatment of eye infections. Sulfathiazole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.It has properties similar to sulfamethoxazole.

SULFAMETHYLTHIAZOLE

R12OZ3O07F

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Status:

Possibly Marketed Outside US

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Bacterial dihydropteroate synthase

Conditions:

Bacterial eye infections

Sulfamethylthiazole is a sulfonamide antibiotic. It is applied topically with tetracycline in the treatment of eye infections.

SUCCINYLSULFATHIAZOLE

RSS8647O4S

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Status:

US Previously Marketed

First approved in 1940

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Escherichia coli

folic acid biosynthetic process

Bacterial dihydropteroate synthase

Escherichia coli

Conditions:

Vaginal infections

Sulfathiazole is a short-acting sulfonamide with properties similar to those of sulfamethoxazole. It is now rarely used systemically due to its toxicity. Sulfathiazole is used with other sulfonamides, usually sulfabenzamide and sulfacetamide, in prep...

arations for the topical treatment of vaginal infections and is also used with other drugs in the treatment of skin infections. Sulfathiazole sodium has been applied topically with other drugs in the treatment of eye infections. Sulfathiazole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.It has properties similar to sulfamethoxazole.

SULPHATHIAZOLE SODIUM PENTAHYDRATE

ST7PF0D71H

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Status:

US Previously Marketed

First approved in 1940

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Escherichia coli

folic acid biosynthetic process

Bacterial dihydropteroate synthase

Escherichia coli

Conditions:

Vaginal infections

Sulfathiazole is a short-acting sulfonamide with properties similar to those of sulfamethoxazole. It is now rarely used systemically due to its toxicity. Sulfathiazole is used with other sulfonamides, usually sulfabenzamide and sulfacetamide, in prep...

arations for the topical treatment of vaginal infections and is also used with other drugs in the treatment of skin infections. Sulfathiazole sodium has been applied topically with other drugs in the treatment of eye infections. Sulfathiazole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.It has properties similar to sulfamethoxazole.

SUCCINYLSULFATHIAZOLE MONOHYDRATE

HM7K18OJZ9

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Status:

US Previously Marketed

First approved in 1940

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Escherichia coli

folic acid biosynthetic process

Bacterial dihydropteroate synthase

Escherichia coli

Conditions:

Vaginal infections

Sulfathiazole is a short-acting sulfonamide with properties similar to those of sulfamethoxazole. It is now rarely used systemically due to its toxicity. Sulfathiazole is used with other sulfonamides, usually sulfabenzamide and sulfacetamide, in prep...

arations for the topical treatment of vaginal infections and is also used with other drugs in the treatment of skin infections. Sulfathiazole sodium has been applied topically with other drugs in the treatment of eye infections. Sulfathiazole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.It has properties similar to sulfamethoxazole.

SULFATHIAZOLE SODIUM MONOHYDRATE

W6NDW4K12P

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Status:

US Previously Marketed

First approved in 1940

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Escherichia coli

folic acid biosynthetic process

Bacterial dihydropteroate synthase

Escherichia coli

Conditions:

Vaginal infections

Sulfathiazole is a short-acting sulfonamide with properties similar to those of sulfamethoxazole. It is now rarely used systemically due to its toxicity. Sulfathiazole is used with other sulfonamides, usually sulfabenzamide and sulfacetamide, in prep...

arations for the topical treatment of vaginal infections and is also used with other drugs in the treatment of skin infections. Sulfathiazole sodium has been applied topically with other drugs in the treatment of eye infections. Sulfathiazole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.It has properties similar to sulfamethoxazole.

SULFATHIAZOLE ZINC

4KCI0QUF9Q

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Status:

US Previously Marketed

First approved in 1940

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Escherichia coli

folic acid biosynthetic process

Bacterial dihydropteroate synthase

Escherichia coli

Conditions:

Vaginal infections

Sulfathiazole is a short-acting sulfonamide with properties similar to those of sulfamethoxazole. It is now rarely used systemically due to its toxicity. Sulfathiazole is used with other sulfonamides, usually sulfabenzamide and sulfacetamide, in prep...

arations for the topical treatment of vaginal infections and is also used with other drugs in the treatment of skin infections. Sulfathiazole sodium has been applied topically with other drugs in the treatment of eye infections. Sulfathiazole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.It has properties similar to sulfamethoxazole.

SULFATHIAZOLE SODIUM

PV16N742VM

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Search for Structure

Status:

US Previously Marketed

First approved in 1940

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Escherichia coli

folic acid biosynthetic process

Bacterial dihydropteroate synthase

Escherichia coli

Conditions:

Vaginal infections

Sulfathiazole is a short-acting sulfonamide with properties similar to those of sulfamethoxazole. It is now rarely used systemically due to its toxicity. Sulfathiazole is used with other sulfonamides, usually sulfabenzamide and sulfacetamide, in prep...

arations for the topical treatment of vaginal infections and is also used with other drugs in the treatment of skin infections. Sulfathiazole sodium has been applied topically with other drugs in the treatment of eye infections. Sulfathiazole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.It has properties similar to sulfamethoxazole.

SULFAMETHYLTHIAZOLE SODIUM

8N35S1D1BL

Export Data
Search for Structure

Status:

Possibly Marketed Outside US

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Bacterial dihydropteroate synthase

Conditions:

Bacterial eye infections

Sulfamethylthiazole is a sulfonamide antibiotic. It is applied topically with tetracycline in the treatment of eye infections.

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