SULFAMETHYLTHIAZOLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H11N3O2S2
Molecular Weight	269.343
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=CSC(NS(=O)(=O)C2=CC=C(N)C=C2)=N1

InChI

InChIKey=KJVQYDYPDFFJMP-UHFFFAOYSA-N

InChI=1S/C10H11N3O2S2/c1-7-6-16-10(12-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)

HIDE SMILES / InChI

Molecular Formula	C10H11N3O2S2
Molecular Weight	269.343
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: www.drugfuture.com/mt/sulfamethoxazole.pdf | http://adisinsight.springer.com/drugs/800047865 | http://www.sifigroup.com/pagineprodotti-Retina/47_5/eng/

Sulfamethylthiazole is a sulfonamide antibiotic. It is applied topically with tetracycline in the treatment of eye infections.

CNS Activity

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Bacterial dihydropteroate synthase 44 Target ID: CHEMBL2364668 Sources: www.drugfuture.com/mt/sulfamethoxazole.pdf \| http://adisinsight.springer.com/drugs/800047865	Inhibitor 8297

Conditions

Condition	Modality	Targets	Highest Phase	Product
Bacterial eye infections 5 Sources: http://adisinsight.springer.com/drugs/800047865	Curative		Approved 8429	PENSULVIT Approved Use Pensulvit (5% Sulfamethylthiazole and 1% tetracycline) ointment is used for the topical treatment of bacterial eye infections.

PubMed

Title	Date	PubMed
CHEMOTHERAPY OF PNEUMOCOCCIC MENINGITIS WITH SPECIAL REFERENCE TO SULFATHIAZOLE.	1942 May	16694913
Determination of sulfathiazole in type C medicated swine feed by reversed-phase liquid chromatography with post-column derivatization.	2003 Jul-Aug	14509417

Patents

Sample Use Guides

In Vivo Use Guide

Pensulvit (5% Sulfamethylthiazole and 1% tetracycline) ointment is used for the topical treatment of bacterial eye infections.

Route of Administration: Topical

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 01:36:15 GMT 2023` Edited by `admin` on `Sat Dec 16 01:36:15 GMT 2023`
Record UNII	R12OZ3O07F
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SULFAMETHYLTHIAZOLE

Common Name

English

4-AMINO-N-(4-METHYL-2-THIAZOLE)BENZENESULFONAMIDE

Common Name

English

4-METHYL-2-SULFANILAMIDOTHIAZOLE

Systematic Name

English

SULFAMETHYLTHIAZOLE [MI]

Common Name

English

Sulfamethylthiazole [WHO-DD]

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID80199481