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Showing 1 - 5 of 5 results

Status:
US Approved Rx (2014)
First approved in 2014

Class (Stereo):
CHEMICAL (ACHIRAL)



Miltefosine is an anti-leishmanial agent. It is an alkyl phospholipids compound, was originally intended for breast cancer and other solid tumors. However, it could not be developed as an oral agent because of dose-limiting gastro-intestinal toxicity...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)

Elbimilast or ronomilast (previously ELB 353) is a phosphodiesterase IV (PDE4) inhibitor. It has been investigated in the treatment of chronic obstructive pulmonary disease.
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)

Elmustine (1-(2-hydroxyethyl)3-(2-chloroethyl)-3-nitrosourea or HECNU) is an alkylating agent with antineoplastic properties. Elmustine is monofunctional and bifunctional alkylating agent that form, in a quantitatively minor reaction, DNA-DNA crossli...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)


Zindoxifene (D 16726 or 5-acetoxy-2-(4-acetoxyphenyl)-1-ethyl-3-methylindole), is an antiestrogenic phenylindole with a high affinity for the estrogen receptor. Zindoxifene exerts inhibiting activity against tumors of prostatic and mammary origins bo...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)


Anpirtoline [D 16949] is a dichloropyridine derivative with antinociceptive and antidepressant activity. Anpirtoline has been described as an agonist at 5-HT1B and 5-HT1D receptors with a relatively high potency. It also acts as an agonist at 5-HT1A ...