ELBIMILAST

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H13Cl2FN4O2
Molecular Weight	443.258
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

FC1=CC=C(CN2C=C(C(=O)C(=O)NC3=C(Cl)C=NC=C3Cl)C4=C2N=CC=C4)C=C1

InChI

InChIKey=JERXUPDBWDWFCF-UHFFFAOYSA-N

InChI=1S/C21H13Cl2FN4O2/c22-16-8-25-9-17(23)18(16)27-21(30)19(29)15-11-28(20-14(15)2-1-7-26-20)10-12-3-5-13(24)6-4-12/h1-9,11H,10H2,(H,25,27,30)

HIDE SMILES / InChI

Molecular Formula	C21H13Cl2FN4O2
Molecular Weight	443.258
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://adisinsight.springer.com/drugs/800013990 | https://english.prescrire.org/Docu/DOCSDCI/EN_20121025PrescrireContributionProposedINNlist107.pdf

Elbimilast or ronomilast (previously ELB 353) is a phosphodiesterase IV (PDE4) inhibitor. It has been investigated in the treatment of chronic obstructive pulmonary disease.

Originator

Approval Year

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:16:18 UTC 2023` Edited by `admin` on `Fri Dec 15 19:16:18 UTC 2023`
Record UNII	F49V1L3QBD
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ELBIMILAST

Official Name

English

1H-PYRROLO(2,3-B)PYRIDINE-3-ACETAMIDE, N-(3,5-DICHLORO-4-PYRIDINYL)-1-((4-FLUOROPHENYL)METHYL-.ALPHA.-OXO-

Common Name

English

N-(3,5-DICHLOROPYRIDIN-4-YL)-2-(1-((4-FLUOROPHENYL)METHYL)-1H-PYRROLO(2,3-B)PYRIDIN-3-YL)-2-OXOACETAMIDE

Systematic Name

English

Ronomilast [WHO-DD]

Common Name

English

AWD-12353

Common Name

English

RONOMILAST

Common Name

English

ELB-353

Common Name

English

ELB353

Common Name

English

elbimilast [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C744