U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 751 - 760 of 772 results

Cobalt is a transition metal, naturally ocurring in the minerals cobaltite, smaltite, and erythrite, and is often associated with nickel, silver, lead, copper, and iron ores, from which it is most frequently obtained as a by-product. Depending on the considered species, cobalt has multiple industrial applications including the production of alloys and hard metal, diamond polishing, drying agents, pigments and catalysts. Cobalt is an essential component of Vitamin B12 (hydroxycolalamin). Cobalt functions as a co-factor in enzyme catalysed reactions and is involved in the production of erythropoietin, a hormone that stimulates the formation of erythrocytes. Cobalt salts were used to treat anemia and stimulate erythropoiesis, but was withdrawn from market since Co(II) cations are genotoxic in vitro and in vivo, and carcinogenic in rodents. Hovewer, Co salts are reported to be used by athletes as a doping
Cobalt is a transition metal, naturally ocurring in the minerals cobaltite, smaltite, and erythrite, and is often associated with nickel, silver, lead, copper, and iron ores, from which it is most frequently obtained as a by-product. Depending on the considered species, cobalt has multiple industrial applications including the production of alloys and hard metal, diamond polishing, drying agents, pigments and catalysts. Cobalt is an essential component of Vitamin B12 (hydroxycolalamin). Cobalt functions as a co-factor in enzyme catalysed reactions and is involved in the production of erythropoietin, a hormone that stimulates the formation of erythrocytes. Cobalt salts were used to treat anemia and stimulate erythropoiesis, but was withdrawn from market since Co(II) cations are genotoxic in vitro and in vivo, and carcinogenic in rodents. Hovewer, Co salts are reported to be used by athletes as a doping
Cobalt is a transition metal, naturally ocurring in the minerals cobaltite, smaltite, and erythrite, and is often associated with nickel, silver, lead, copper, and iron ores, from which it is most frequently obtained as a by-product. Depending on the considered species, cobalt has multiple industrial applications including the production of alloys and hard metal, diamond polishing, drying agents, pigments and catalysts. Cobalt is an essential component of Vitamin B12 (hydroxycolalamin). Cobalt functions as a co-factor in enzyme catalysed reactions and is involved in the production of erythropoietin, a hormone that stimulates the formation of erythrocytes. Cobalt salts were used to treat anemia and stimulate erythropoiesis, but was withdrawn from market since Co(II) cations are genotoxic in vitro and in vivo, and carcinogenic in rodents. Hovewer, Co salts are reported to be used by athletes as a doping
Clove oil is a natural product, derived from the Eugenia caryophyllata tree. Clove oil is 85 to 95% eugenol. Isoeugenol and methyleugenol make up 5 to 15% of the remaining ingredients. Isoeugenol is manufactured from eugenol by a process of isomerization. Isoeugenol have been used in foods and eugenol has been used in animal feeds. Isoeugenol is used as a fish anesthetic. The mechanism of action of isoeugenol in fish has not been determined. It is hypothesised that its effects are mediated via receptors controlling cellular ion channels in a similar way to that described for local anaesthetics. Reports of adverse reactions involving the use of isoeugenol in humans are primarily confined to incidents of contact sensitization or allergy following dermal exposure.
mixture
Status:
US Approved Allergenic Extract (1994)

Class:
MIXTURE


Quaternium-15, a preservative, is one of the most used substances and is added to several cosmetics and other industrial products. Quaternium-15 is a mixture of isomers, where the cis-form is the dominant form and where the trans-form is the minor component present as an impurity. Quaternium-15 can be found under a variety of names, most commonly those of the Dow Chemical Company: Dowicil 200 (cis isomer only), Dowicil 75 and Dowicil 100 (both a mix of cis and trans isomers). The isolated cis-compound is used primarily in cosmetic applications, with a maximum permitted concentration in the EU of 0.2%. DOWICIL 200 preservative (cis form) is used primarily as a preservative in a wide variety of personal-care and cosmetic products. It is designed to provide highly effective broad-spectrum antimicrobial activity, especially in water-based formulations. It is used in both leave-on and rinse-off application such as baby-care products, hair-care products, lotions, powders, and creams. The mixed product (cis- and trans-) is used in a wider range of formulations such as: emulsifiable metal-cutting fluids; latex and emulsion paints; liquid floor polishes and floor waxes; glues and adhesives. Recently, the cis-form has been classified as a CMR substance with the classification toxic to reproduction, category 3. This classification only concerns the cis-isomer:
mixture
Status:
US Approved Allergenic Extract (1994)

Class:
MIXTURE

Conditions:

Gold monoiodide (AuI; Aurum iodatum) is a chemical compound of gold and iodine. This compound can be synthesized by heating gold and iodine in a sealed tube at 120°C for about four months. It decomposes when treated with hot water, but its related complexes are much more stable. It’s used like unapproved homeopathic product for treatment of Senile Paresis. This product is to be used for self-limiting conditions. If symptoms do not improve in 4 days, or worsen, discontinue use and seek assistance of health professional
mixture
Status:
US Approved Allergenic Extract (1994)

Class:
MIXTURE

alpha-Amyl cinnamaldehyde is a pale yellow liquid fragrance material with a floral smell used in allergenic testing.
structurally diverse
Status:
US Approved Allergenic Extract

Class:
STRUCTURALLY DIVERSE

structurally diverse
Status:
US Approved Allergenic Extract (1981)

Class:
STRUCTURALLY DIVERSE

structurally diverse
Status:
US Approved Allergenic Extract (1981)

Class:
STRUCTURALLY DIVERSE

Showing 751 - 760 of 772 results