Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | 2C6H11O7.Co |
| Molecular Weight | 449.2279 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 8 / 8 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Co++].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O
InChI
InChIKey=BMJZVKPTRWYLKB-IYEMJOQQSA-L
InChI=1S/2C6H12O7.Co/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;/h2*2-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1
| Molecular Formula | Co |
| Molecular Weight | 58.933195 |
| Charge | 2 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C6H11O7 |
| Molecular Weight | 195.1473 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
DescriptionSources: ISBN 9780873715980, Foden C.R., Weddell J.L., 'Hazardous Materials: Emergency Action Data' (1991), Retrieved from https://books.google.com/books?id=4IPE8Pjhm8UC&pghttps://fscimage.fishersci.com/msds/05330.htmhttp://datasheets.scbt.com/sc-227251.pdfISBN: 978-94-010-7024-9, Matar M.S., Mirbach M.J.,Tayim H.A. 'Catalysis in Petrochemical Processes' (1988), p.136, Retrieved from https://books.google.com/books?id=MkD2JnDkZYYC&dqhttp://aygrt.isrj.org/colorArticles/4972.pdfhttp://laboratorychemicals.in/uploads/msds/10026-17-2-49128.pdfhttps://www.ncbi.nlm.nih.gov/pubmed/2253206http://onlinelibrary.wiley.com/doi/10.1002/3527600418.mb744048e0023/pdfhttps://www.ncbi.nlm.nih.gov/pubmed/27527840https://monographs.iarc.fr/ENG/Monographs/vol52/mono52-16.pdfhttps://pubchem.ncbi.nlm.nih.gov/compound/104729Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/14643417 | https://www.ncbi.nlm.nih.gov/pubmed/16244201
Sources: ISBN 9780873715980, Foden C.R., Weddell J.L., 'Hazardous Materials: Emergency Action Data' (1991), Retrieved from https://books.google.com/books?id=4IPE8Pjhm8UC&pghttps://fscimage.fishersci.com/msds/05330.htmhttp://datasheets.scbt.com/sc-227251.pdfISBN: 978-94-010-7024-9, Matar M.S., Mirbach M.J.,Tayim H.A. 'Catalysis in Petrochemical Processes' (1988), p.136, Retrieved from https://books.google.com/books?id=MkD2JnDkZYYC&dqhttp://aygrt.isrj.org/colorArticles/4972.pdfhttp://laboratorychemicals.in/uploads/msds/10026-17-2-49128.pdfhttps://www.ncbi.nlm.nih.gov/pubmed/2253206http://onlinelibrary.wiley.com/doi/10.1002/3527600418.mb744048e0023/pdfhttps://www.ncbi.nlm.nih.gov/pubmed/27527840https://monographs.iarc.fr/ENG/Monographs/vol52/mono52-16.pdfhttps://pubchem.ncbi.nlm.nih.gov/compound/104729
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/14643417 | https://www.ncbi.nlm.nih.gov/pubmed/16244201
Cobalt is a transition metal, naturally ocurring in the minerals cobaltite, smaltite, and erythrite, and is often associated with nickel, silver, lead, copper, and iron ores, from which it is most frequently obtained as a by-product. Depending on the considered species, cobalt has multiple industrial applications including the production of alloys and hard metal, diamond polishing, drying agents, pigments and catalysts. Cobalt is an essential component of Vitamin B12 (hydroxycolalamin). Cobalt functions as a co-factor in enzyme catalysed reactions and is involved in the production of erythropoietin, a hormone that stimulates the formation of erythrocytes. Cobalt salts were used to treat anemia and stimulate erythropoiesis, but was withdrawn from market since Co(II) cations are genotoxic in vitro and in vivo, and carcinogenic in rodents. Hovewer, Co salts are reported to be used by athletes as a doping
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Differential pulmonary effects of CoO and La2O3 metal oxide nanoparticle responses during aerosolized inhalation in mice. | 2016-08-15 |
|
| In vitro evaluation of anticancer and antibacterial activities of cobalt oxide nanoparticles. | 2015-12 |
|
| Purification and characterization of glucose 6-phosphate dehydrogenase enzyme from rainbow trout (Oncorhynchus mykiss) liver and investigation of the effects of some metal ions on enzyme activity. | 2015-05 |
|
| In vitro assessment of cobalt oxide particle toxicity: identifying and circumventing interference. | 2013-09 |
|
| Expression of surface markers on the human monocytic leukaemia cell line, THP-1, as indicators for the sensitizing potential of chemicals. | 2009-04 |
|
| Synthesis and antifungal potential of Co(II) complexes of 1-(2'-hydroxyphenyl) ethylideneanilines. | 2006-02 |
|
| Effect of desferrioxamine and metals on the hydroxylases in the oxygen sensing pathway. | 2005-08 |
|
| Cobalt and antimony: genotoxicity and carcinogenicity. | 2003-12-10 |
|
| Determination of trace metal ions in common salt by stripping voltammetry. | 1999-12-10 |
|
| Synthesis and Anti-Candida Activity of Cobalt(II) Complexes of Benzene-1,2-Dioxyacetic Acid (bdoaH(2)). X-Ray Crystal Structures of [Co(bdoa)(H(2)O)(3)] 3.5H(2)O and {[CO(phen)(3)](bdoa)}(2)24H(2)O (phen = 1,10-Phenanthroline). | 1999 |
|
| Carcinogenic sulfide salts of nickel and cadmium induce H2O2 formation by human polymorphonuclear leukocytes. | 1990-12-01 |
|
| Inhalation toxicity studies of cobalt sulfate in F344/N rats and B6C3F1 mice. | 1990-08 |
|
| Improved methods for cobalt filling and silver intensification of insect motor neurons. | 1982-07 |
|
| Acute oral toxicity of inorganic cobalt compounds in rats. | 1982-06 |
|
| Cobalt iontophoresis techniques for tracing afferent and efferent connections in the vertebrate CNS. | 1975-05-02 |
|
| Erythropoietic effect of cobalt in patients with or without anemia. | 1949-05-12 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:03:17 GMT 2025
by
admin
on
Mon Mar 31 18:03:17 GMT 2025
|
| Record UNII |
26SK597UWV
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
DSLD |
42 (Number of products:65)
Created by
admin on Mon Mar 31 18:03:17 GMT 2025 , Edited by admin on Mon Mar 31 18:03:17 GMT 2025
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
26SK597UWV
Created by
admin on Mon Mar 31 18:03:17 GMT 2025 , Edited by admin on Mon Mar 31 18:03:17 GMT 2025
|
PRIMARY | |||
|
DTXSID60222241
Created by
admin on Mon Mar 31 18:03:17 GMT 2025 , Edited by admin on Mon Mar 31 18:03:17 GMT 2025
|
PRIMARY | |||
|
71957-08-9
Created by
admin on Mon Mar 31 18:03:17 GMT 2025 , Edited by admin on Mon Mar 31 18:03:17 GMT 2025
|
PRIMARY | |||
|
276-206-1
Created by
admin on Mon Mar 31 18:03:17 GMT 2025 , Edited by admin on Mon Mar 31 18:03:17 GMT 2025
|
PRIMARY | |||
|
SUB13409MIG
Created by
admin on Mon Mar 31 18:03:17 GMT 2025 , Edited by admin on Mon Mar 31 18:03:17 GMT 2025
|
PRIMARY | |||
|
26SK597UWV
Created by
admin on Mon Mar 31 18:03:17 GMT 2025 , Edited by admin on Mon Mar 31 18:03:17 GMT 2025
|
PRIMARY | |||
|
6451600
Created by
admin on Mon Mar 31 18:03:17 GMT 2025 , Edited by admin on Mon Mar 31 18:03:17 GMT 2025
|
PRIMARY | |||
|
235987
Created by
admin on Mon Mar 31 18:03:17 GMT 2025 , Edited by admin on Mon Mar 31 18:03:17 GMT 2025
|
PRIMARY | RxNorm | ||
|
100000076293
Created by
admin on Mon Mar 31 18:03:17 GMT 2025 , Edited by admin on Mon Mar 31 18:03:17 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
PARENT -> SALT/SOLVATE | |||
|
|
PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |