Glycerophosphoinositol choline is a salt of glycerophosphoinositol and choline. It is used in cream or emollient formulation in the treatment of irritative and allergic dermatitis and xerosis of the skin. Glycerophosphoinositol is a natural metabolite, produced in the organism through deacylation by phospholipase B of the essential phospholipid phosphatidylinositol. Glycerophosphoinositols are involved in control of signalling enzymes (e.g. adenylyl cyclase), in actin cytoskeleton organization, in invasion of the extracellular matrix by melanoma and breast carcinoma cell lines, and in the control of cell proliferation in epithelial cells.

Crocin is the chemical constituent isolated from the Saffron, the dried trifid stigma of the plant Crocus sativus L. and also from the fruits of Gardenia(Gardenia jasminoides Ellis) Of the carotenoids present in saffron, highly water-soluble crocin (mono and diglycosyl esters of a polyene dicarboxylic acid, named crocetin) is responsible for the majority of its color, and appears to possess various health-promoting properties, as an antioxidant, antitumor, memory enhancer, antidepressant, anxiolytic and aphrodisiac. It is also worth noting that the crocin principle of saffron exhibited high efficacy along with no major toxicity in experimental models. A proteomic study revealed that crocin physically binds to a wide range of cellular proteins such as structural proteins, membrane transporters, and enzymes involved in ATP and redox homeostasis and signal transduction. CROCIN RICH products provide highly purified natural crocin as dietary supplements, they are the purest and most effective formulation of crocin available.