4LSC379 (D159687) is a small-molecule allosteric modulators of PDE4D that do not completely inhibit enzymatic activity. It has reduced potential to cause emesis, while maintaining biological activity in cellular and in vivo models.

12β-Acetoxycimigenol 3-O-β-D-xylanopyranoside is a triterpenoid glycoside extracted from roots Cimicifuga racemosa, a plant used to treat a variety of ailments, including diarrhea, sore throat, rheumatism and menopausal disorders. The compound was also found in the roots of Actaea pachypoda and Cimicifuga fetida. The compound showed weak antibacterial activity in the agar diffusion assay and did not show any cytotoxicity against five human cancer cell lines.

MG-132, also known as carbobenzoxy-Leu-Leu-leucinal, is a peptide aldehyde, which effectively blocks the proteolytic activity of the 26S proteasome complex. It also strongly inhibited calpain activity in vitro. MG-132 is used as a tool for perturbing the proteasome-regulated degradation of intracellular proteins.

3,5-dihydroxyphenylglycine (3,5-DHPG) was the first agonist shown to be specific to the group I metabotropic glutamate receptors, mGluR1 and mGluR5 with its agonist effects residing exclusively in the S-isomer. Some studies suggested a therapeutic role for (S)-3,5-DHPG in neuronal injury, regulation of intestinal motility and secretion, learning and memory processes and in the cardiovascular system. (S)-3,5-DHPG may be useful as a cognitive enhancing agent in memory impairment associated with ischemia or hypoxia.

There is no information about biological and pharmacological application of lead selenite.

D-Araboflavin is an antagonist of riboflavin. Its 200 ug/day decreases the rate of growth of rats, receiving 7 ug of riboflavin/day to such an extent that was no growth by the third week.

N-stearoyl sphingomyelin or stearoyl-sphingomyelin, a minor sphingomyelin component found in milk, is classified as a member of the Phosphosphingolipids. Sphingomyelin has a high affinity for cholesterol and these two lipids pack tightly into liquid-ordered domains among a liquid-disordered phase to form lipid rafts.

There is no information related to the biological and pharmacological application of estradiol 17-phosphate.

Magnesium selenite is soluble selenite salt, that can be used as food additive for the prevention of osteoporosis. There is no information about biological and pharmacological application of Magnesium selenite.

Potassium p-phenolsulfonate is used in spectrophotometric studies. It is a good buffer for the pH range of 8.4 to 9.2 and for spectrophotometric studies of metacresolsulfonphthalein and thymolsulfonphthalein.