A-796260 is a compound that acts as a potent and selective cannabinoid CB2 receptor agonist. The analgesic effects of A-796260 on activity-induced pain behavior were evaluated in a rat model, the results demonstrated that A-796260 may be a useful new pharmacological compound for further studying CB2 receptor pharmacology and for evaluating its role in the modulation of pain.

Epinephrine 4-sulfate is Epinephrine natural metabolite, that can be used for determination of catecholamine sulfoconjugate isomers in normal human urine.

Epiestradiol is an estradiol isomer with weak estrogenic activity.

Magnesium bromate is a white crystalline compound, insoluble in alcohol, soluble in water. Contact may cause irritation to skin, eyes, and mucous membranes. May be toxic by ingestion, inhalation and skin absorption. It is used as an analytical reagent. Has found little usage in Industry because there are better oxidizing agents available.

D-kynurenine is metabolite of the amino acid D-tryptophan. D-kynurenine is an agonist for GPR109B (HM74), a putative G protein-coupled receptor. D-kynurenine elicits chemotactic responses in human neutrophils through GPR109B. D-amino acid oxidase can metabolize D-kynurenine to produce the fluorescent compound kynurenic acid.

A lignan derivative, (-)-(7R, 8S)-dihydrodehydrodiconiferyl alcohol (DHDA), was isolated from Kalopanax septemlobus L. and was observed to have neuritogenic activity. DHDA at 50 uM caused a marked induction of neurite outgrowth and an enhancement of nerve growth factor (NGF)-mediated neurite outgrowth from PC12 cells by amplifying up-stream steps such as MAPK and PKC.

(R)-Ambrisentan is R-isomer impurity of a nonpeptide endothelin ETA receptor antagonist Ambrisentan.

Darusentan is a mixture of two isomers R and S. It was investigated whether darusentan was a potent inhibitor of endothelin signaling and function in both large and small arteries. And it was revealed, that R-isomer was inactive, it didn’t have any binding activity to the endothelin receptor of the rat aortic vascular smooth muscle cells (RAVSMs) membrane in comparison with S-isomer. In addition, in isolated endothelium-denuded rat aortic rings, (S)-darusentan inhibited endothelin-induced vascular contractility, but (R)-darusentan had no effect.

Lead bromate is inorganic salt, that can be used for prevention corrosion by CO2

Darusentan is a mixture of two isomers R and S, the last enantiomer is responsible for the therapeutic properties.