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Details

Stereochemistry RACEMIC
Molecular Formula C18H24O2
Molecular Weight 272.382
Optical Activity ( + / - )
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ISOESTRADIOL, (±)-

SMILES

C[C@]12CC[C@H]3[C@H](CCC4=CC(O)=CC=C34)[C@@H]1CC[C@@H]2O

InChI

InChIKey=VOXZDWNPVJITMN-FPSMNIFISA-N
InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15+,16+,17+,18+/m1/s1

HIDE SMILES / InChI

Description
Curator's Comment: The description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/6479318 | https://www.ncbi.nlm.nih.gov/pubmed/3899717

Epiestradiol is an estradiol isomer with weak estrogenic activity.

Originator

Serini, A.|Logemann, W.
2
Sources: Berichte der Deutschen Chemischen Gesellschaft [Abteilung] B: Abhandlungen (1938), 71B, 186-91.

Approval Year

Unknown
149124
Targets

Targets

Primary TargetPharmacologyConditionPotency
Agonist
2752
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
[Pharmacological activity of modified analogs of steroid estrogens. Racemic 8-isoestradiol].
1984 Jul-Aug
Patents

Patents

WO2014131891
2

Sample Use Guides

In Vivo Use Guide
Rats were treated with 0.5mk/kg for 30 days
Route of Administration: Oral
In Vitro Use Guide
Unknown
Name Type Language
ISOESTRADIOL, (±)-
Common Name English
(±)-8-ISOESTRADIOL
Preferred Name English
ISOESTRADIOL DL-FORM [MI]
Common Name English
ESTRA-1,3,5(10)-TRIENE-3,17-DIOL, (8.ALPHA.,17.BETA.)-(±)-
Systematic Name English
(8.ALPHA.,17.BETA.)-ESTRA-1,3,5(10)-TRIENE-3,17-DIOL, (±)-
Systematic Name English
DL-8-ISO-3,17.BETA.-ESTRADIOL
Common Name English
DL-8-ISOESTRADIOL
Common Name English
Code System Code Type Description
CAS
19669-82-0
Created by admin on Mon Mar 31 22:58:43 GMT 2025 , Edited by admin on Mon Mar 31 22:58:43 GMT 2025
PRIMARY
FDA UNII
1BAQ18C647
Created by admin on Mon Mar 31 22:58:43 GMT 2025 , Edited by admin on Mon Mar 31 22:58:43 GMT 2025
PRIMARY
MERCK INDEX
m6482
Created by admin on Mon Mar 31 22:58:43 GMT 2025 , Edited by admin on Mon Mar 31 22:58:43 GMT 2025
PRIMARY Merck Index
SUBSTANCE RECORD
Structure of ISOESTRADIOL, (±)-
NIH
NCATS
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