(2R,3S)-N-Benzoyl-3-phenylisoserine (also known as the “taxol side chain”) is a structural component of the antimicrotubular drug paclitaxel.

POPC is a 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine. It is an important phospholipid for biophysical experiments and has been used to study various subjects such as lipid rafts. POPC also used in systems mimicking the cell membrane. It was shown that endogenous lipid synthesis generates a discrete phosphatidylcholine species, 1-palmitoyl 2-oleyl phosphatidylcholine (16:0/18:1 PC), that serves as an endogenous ligand for PPARalpha. Myelin is a membrane characterized by high lipid content to facilitate impulse propagation. Changes in myelin fatty acid (FA) composition have been associated with peripheral neuropathy. It was also found that mice lacking sterol regulatory element-binding factor-1c (Srebf1c) have blunted peripheral nerve FA synthesis that results in development of peripheral neuropathy. Peripheral nerves lacking Srebf1c show decreased FA synthesis and glycolytic flux, but increased FA catabolism and mitochondrial function. These metabolic alterations are the result of local accumulation of two endogenous peroxisome proliferator-activated receptor-α (PARalpha) ligands, 1-palmitoyl-2-oleyl-sn-glycerol-3-phosphatidylcholine and 1-stearoyl-2-oleyl-sn-glycerol-3-phosphatidylcholine. Treatment with a PPARalpha antagonist rescues the neuropathy.

Lopinavir, (2R) Epimer, a selective HIV protease inhibitor, possesses similar properties with lopinavir.

Lopinavir, (2R) Epimer, a selective HIV protease inhibitor, possesses similar properties with lopinavir.

Ethyl 2-oxo-4-phenylbutyrate is useful for the synthesis of the important chiral precursor for angiotensin-converting enzyme (ACE) inhibitors.

(S)-bentamapimod is the enantiomer of Bentamapimod (AS-602801 or PGL-5), a JNK mitogen-activated protein kinase inhibitor. No data regarding stereospecificity of the pharmacological activity of bentamapimod enantiomers available.

6',7'-Dihydroxybergamottin is a natural furanocoumarin found principally in grapefruit juice. Along with the chemically related compound bergamottin, it is believed to be responsible for a number of grapefruit–drug interactions, in which the consumption of the juice affects the metabolism of a variety of pharmaceutical drugs.

Phenethyl salicylate is a fragrance ingredient used in many fragrance compounds. The general type of odor of phenethyl salicylate is honey. It may be found in fragrances used in decorative cosmetics, fine fragrances, shampoos, toilet soaps and other toiletries as well as in non-cosmetic products such as household cleaners and detergents. Phenethyl salicylate was approved by the Food and Drug Administration as a flavor. Flavor and Extract Manufacturers’ Association recognized it as safe ingredient. The uterine weights were also significantly increased (P < 0.05) in mice who received 33.3 mg/kg/day phenethyl salicylate. This result suggests that phenethyl salicylate might exert its estrogenic activities in animals or humans.

Clofop (clofop-isobutyl) is a post-emergence herbicide effective against annual grasses such as Alopecurus myosuroides, Echinochloa crus-galli, Eleusine, Panicum and Setaria spp. WHO lists Clofop as obsolete as a pesticide ingredient.

There is no information in the scientific papers related to the biological and pharmacological properties of the diastereomer of lopinavir, LOPINAVIR, (2R,4R)-diastereomer.