Inxight Drugs

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

This repository is under review for potential modification in compliance with Administration directives.

Return Home Inxight Drugs

Home
Browse Drugs
Search
- Structure Search
- Sequence Search
Downloads
About

Show Filters

Hide Filters

Condition

Cyclitis

21

Unknown

2,596

Pain

619

Cancer

609

Hypertension

575

All Match

Any Match

Exclude Selected

Exclude Selected

Development Status

US Approved Rx

21

All Match

Any Match

Exclude Selected

Exclude Selected

Primary Target

Glucocorticoid receptor

21

Mineralocorticoid receptor

21

All Match

Any Match

Exclude Selected

Exclude Selected

Highest Phase

Approved

21

All Match

Any Match

Exclude Selected

Exclude Selected

Approval Year

1958

21

All Match

Any Match

Exclude Selected

Exclude Selected

Treatment Modality

Primary

21

All Match

Any Match

Exclude Selected

Exclude Selected

CNS Activity

CNS Penetrant

21

All Match

Any Match

Exclude Selected

Exclude Selected

Originator

Arth, G.E. et al.

21

All Match

Any Match

Exclude Selected

Exclude Selected

Substance Class

Chemical

20

Mixture

1

All Match

Any Match

Exclude Selected

Exclude Selected

Code System

FDA UNII

21

CAS

20

PUBCHEM

20

EPA CompTox

19

SMS_ID

15

All Match

Any Match

Exclude Selected

Exclude Selected

ATC Level 1

ALIMENTARY TRACT AND METABOLISM

1

CARDIOVASCULAR SYSTEM

1

DERMATOLOGICALS

1

RESPIRATORY SYSTEM

1

SENSORY ORGANS

1

All Match

Any Match

Exclude Selected

Exclude Selected

ATC Level 2

ANTI-ACNE PREPARATIONS

1

CORTICOSTEROIDS FOR SYSTEMIC USE

1

CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS

1

NASAL PREPARATIONS

1

OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS

1

All Match

Any Match

Exclude Selected

Exclude Selected

ATC Level 3

AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE

1

ANTI-ACNE PREPARATIONS FOR TOPICAL USE

1

ANTIINFLAMMATORY AGENTS

1

ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION

1

CORTICOSTEROIDS

1

All Match

Any Match

Exclude Selected

Exclude Selected

ATC Level 4

Corticosteroids

1

Corticosteroids and antiinfectives in combination

1

Corticosteroids for local oral treatment

1

Corticosteroids, combinations for treatment of acne

1

Corticosteroids, moderately potent (group II)

1

All Match

Any Match

Exclude Selected

Exclude Selected

Substance Form

Salts, Hydrates, Esters, etc.

20

Principal Form

1

All Match

Any Match

Exclude Selected

Exclude Selected

Showing 1 - 10 of 21 results

First page disabled
Previous page disabled
1
Next page
Next page

DEXAMETHASONE

7S5I7G3JQL

Export Data
Search for Structure

Status:

US Approved Rx (2018)

First approved in 1958

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Glucocorticoid receptor

Mineralocorticoid receptor

Glucocorticoid receptor

Conditions:

Multiple myeloma

Herpes zoster keratitis

Allergic conjunctivitis

Superficial punctate keratitis

Bacterial conjunctivitis

Dexamethasone is an anti-inflammatory agent that is FDA approved for the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling and othe...

rs. Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. Adverse reactions are: Glaucoma with optic nerve damage, visual acuity and field defects; cataract formation; secondary ocular infection following suppression of host response; and perforation of the globe may occur; muscle weakness; osteoporosis and others. Aminoglutethimide may diminish adrenal suppression by corticosteroids. Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance.

Dexamethasone 21-sulfate

VMN9Z37FQR

Export Data
Search for Structure

Status:

US Approved Rx (2018)

First approved in 1958

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Glucocorticoid receptor

Mineralocorticoid receptor

Glucocorticoid receptor

Conditions:

Multiple myeloma

Herpes zoster keratitis

Allergic conjunctivitis

Superficial punctate keratitis

Bacterial conjunctivitis

Dexamethasone is an anti-inflammatory agent that is FDA approved for the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling and othe...

rs. Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. Adverse reactions are: Glaucoma with optic nerve damage, visual acuity and field defects; cataract formation; secondary ocular infection following suppression of host response; and perforation of the globe may occur; muscle weakness; osteoporosis and others. Aminoglutethimide may diminish adrenal suppression by corticosteroids. Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance.

DEXAMETHASONE SODIUM SUCCINATE

UZA9VMT64W

Export Data
Search for Structure

Status:

US Approved Rx (2018)

First approved in 1958

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Glucocorticoid receptor

Mineralocorticoid receptor

Glucocorticoid receptor

Conditions:

Multiple myeloma

Herpes zoster keratitis

Allergic conjunctivitis

Superficial punctate keratitis

Bacterial conjunctivitis

Dexamethasone is an anti-inflammatory agent that is FDA approved for the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling and othe...

rs. Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. Adverse reactions are: Glaucoma with optic nerve damage, visual acuity and field defects; cataract formation; secondary ocular infection following suppression of host response; and perforation of the globe may occur; muscle weakness; osteoporosis and others. Aminoglutethimide may diminish adrenal suppression by corticosteroids. Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance.

DEXAMETHASONE SUCCINATE

9UY5TBO121

Export Data
Search for Structure

Status:

US Approved Rx (2018)

First approved in 1958

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Glucocorticoid receptor

Mineralocorticoid receptor

Glucocorticoid receptor

Conditions:

Multiple myeloma

Herpes zoster keratitis

Allergic conjunctivitis

Superficial punctate keratitis

Bacterial conjunctivitis

Dexamethasone is an anti-inflammatory agent that is FDA approved for the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling and othe...

rs. Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. Adverse reactions are: Glaucoma with optic nerve damage, visual acuity and field defects; cataract formation; secondary ocular infection following suppression of host response; and perforation of the globe may occur; muscle weakness; osteoporosis and others. Aminoglutethimide may diminish adrenal suppression by corticosteroids. Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance.

DEXAMETHASONE 21-VALERATE

F2EHP3G50P

Export Data
Search for Structure

Status:

US Approved Rx (2018)

First approved in 1958

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Glucocorticoid receptor

Mineralocorticoid receptor

Glucocorticoid receptor

Conditions:

Multiple myeloma

Herpes zoster keratitis

Allergic conjunctivitis

Superficial punctate keratitis

Bacterial conjunctivitis

Dexamethasone is an anti-inflammatory agent that is FDA approved for the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling and othe...

rs. Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. Adverse reactions are: Glaucoma with optic nerve damage, visual acuity and field defects; cataract formation; secondary ocular infection following suppression of host response; and perforation of the globe may occur; muscle weakness; osteoporosis and others. Aminoglutethimide may diminish adrenal suppression by corticosteroids. Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance.

DEXAMETHASONE SODIUM SULFATE

41B47ECP9F

Export Data
Search for Structure

Status:

US Approved Rx (2018)

First approved in 1958

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Glucocorticoid receptor

Mineralocorticoid receptor

Glucocorticoid receptor

Conditions:

Multiple myeloma

Herpes zoster keratitis

Allergic conjunctivitis

Superficial punctate keratitis

Bacterial conjunctivitis

Dexamethasone is an anti-inflammatory agent that is FDA approved for the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling and othe...

rs. Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. Adverse reactions are: Glaucoma with optic nerve damage, visual acuity and field defects; cataract formation; secondary ocular infection following suppression of host response; and perforation of the globe may occur; muscle weakness; osteoporosis and others. Aminoglutethimide may diminish adrenal suppression by corticosteroids. Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance.

DEXAMETHASONE METASULFOBENZOATE

C67221CB9Q

Export Data
Search for Structure

Status:

US Approved Rx (2018)

First approved in 1958

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Glucocorticoid receptor

Mineralocorticoid receptor

Glucocorticoid receptor

Conditions:

Multiple myeloma

Herpes zoster keratitis

Allergic conjunctivitis

Superficial punctate keratitis

Bacterial conjunctivitis

Dexamethasone is an anti-inflammatory agent that is FDA approved for the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling and othe...

rs. Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. Adverse reactions are: Glaucoma with optic nerve damage, visual acuity and field defects; cataract formation; secondary ocular infection following suppression of host response; and perforation of the globe may occur; muscle weakness; osteoporosis and others. Aminoglutethimide may diminish adrenal suppression by corticosteroids. Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance.

DEXAMETHASONE 21-METHANESULFONATE

O9S11FMA79

Export Data
Search for Structure

Status:

US Approved Rx (2018)

First approved in 1958

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Glucocorticoid receptor

Mineralocorticoid receptor

Glucocorticoid receptor

Conditions:

Multiple myeloma

Herpes zoster keratitis

Allergic conjunctivitis

Superficial punctate keratitis

Bacterial conjunctivitis

Dexamethasone is an anti-inflammatory agent that is FDA approved for the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling and othe...

rs. Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. Adverse reactions are: Glaucoma with optic nerve damage, visual acuity and field defects; cataract formation; secondary ocular infection following suppression of host response; and perforation of the globe may occur; muscle weakness; osteoporosis and others. Aminoglutethimide may diminish adrenal suppression by corticosteroids. Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance.

DEXAMETHASONE DIPROPIONATE

K3UKR54YXW

Export Data
Search for Structure

Status:

US Approved Rx (2018)

First approved in 1958

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Glucocorticoid receptor

Mineralocorticoid receptor

Glucocorticoid receptor

Conditions:

Multiple myeloma

Herpes zoster keratitis

Allergic conjunctivitis

Superficial punctate keratitis

Bacterial conjunctivitis

Dexamethasone is an anti-inflammatory agent that is FDA approved for the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling and othe...

rs. Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. Adverse reactions are: Glaucoma with optic nerve damage, visual acuity and field defects; cataract formation; secondary ocular infection following suppression of host response; and perforation of the globe may occur; muscle weakness; osteoporosis and others. Aminoglutethimide may diminish adrenal suppression by corticosteroids. Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance.

DEXAMETHASONE ACETATE ANHYDROUS

K7V8P532WP

Export Data
Search for Structure

Status:

US Approved Rx (2018)

First approved in 1958

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Glucocorticoid receptor

Mineralocorticoid receptor

Glucocorticoid receptor

Conditions:

Multiple myeloma

Herpes zoster keratitis

Allergic conjunctivitis

Superficial punctate keratitis

Bacterial conjunctivitis

Dexamethasone is an anti-inflammatory agent that is FDA approved for the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling and othe...

rs. Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. Adverse reactions are: Glaucoma with optic nerve damage, visual acuity and field defects; cataract formation; secondary ocular infection following suppression of host response; and perforation of the globe may occur; muscle weakness; osteoporosis and others. Aminoglutethimide may diminish adrenal suppression by corticosteroids. Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance.

Showing 1 - 10 of 21 results

First page disabled
Previous page disabled
1
Next page
Next page

HHS VULNERABILITY DISCLOSURE

For language access assistance, contact the NCATS Public Information Officer

National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966


			version 1.1