U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 2771 - 2780 of 149123 results

Status:
Investigational
Source:
NCT01664143: Phase 1 Interventional Completed Healthy Volunteer
(2012)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
USAN:SCOPAFUNGIN [USAN]
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Scopafungin (also known as GE4800) is an inhibitor of oxidative phosphorylation in mitochondria. Scopafungin also inhibits, in vitro, a variety of pathogenic fungi, yeasts, and gram-positive bacteria.
Status:
Investigational
Source:
INN:metindizate
Source URL:

Class (Stereo):
CHEMICAL (MIXED)

Metindizate was developed as a spasmolytic agent. Information about the current use of this compound is not available.
Status:
Investigational
Source:
NCT01230749: Phase 2 Interventional Completed Diabetes Mellitus, Type 2
(2010)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

JNJ-41443532 is a C-C motif chemokine receptor 2 antagonist. It is under development for the treatment of type 2 diabetes.
Status:
Investigational
Source:
NCT02193958: Phase 1/Phase 2 Interventional Completed AML
(2014)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Status:
Investigational
Source:
NCT01174927: Phase 1 Interventional Completed Opiate
(2010)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Diallylmelamine was tested in man as a gastric antisecretory agent. In these tests it was inactive. However, when this compound was administered to trained, unanesthetized dogs, it was surprisingly found to have pronounced and prolonged hypotensive activity. Diallylmelamine is an effective hypotensive agent in hypertensive dogs and rats, having a duration of action exceeding twenty-four hours from a single oral dose. It has limited efficacy in normotensive rats. Hypotensive activity of gradual onset is preceded by a latent period of up to two hours and becomes maximal six hours or more after dosing. This agent does not depress cardiac output or sympathetic vasoconstrictor activity.
Status:
Investigational
Source:
NCT02332720: Phase 2 Interventional Completed Hepatitis C
(2015)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Ruzasvir (previously known as MK-8408) was developed as a nonstructural protein 5A (NS5A) inhibitor for the treatment of hepatitis C and hepatitis C infection. Ruzasvir successfully completed phase II clinical trial for combination therapy. The obtained results have shown that ruzasvir in combination with uprifosbuvir was highly effective and well-tolerated in participants infected with hepatitis C virus genotypes GT1, GT2, GT4, GT5, and GT6, with a lower efficacy in GT3-infected persons.
Status:
Investigational
Source:
NCT03701308: Phase 2/Phase 3 Interventional Active, not recruiting Acute Myeloid Leukemia
(2019)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
JAN:TERALLETHRIN [JAN]
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Terallethrin is an insecticide that controls flying insects including houseflies, wasps and mosquitoes.

Showing 2771 - 2780 of 149123 results