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Details

Stereochemistry ACHIRAL
Molecular Formula C9H14N6
Molecular Weight 206.2477
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIALLYLMELAMINE

SMILES

NC1=NC(=NC(N)=N1)N(CC=C)CC=C

InChI

InChIKey=ROHTVIURAJBDES-UHFFFAOYSA-N
InChI=1S/C9H14N6/c1-3-5-15(6-4-2)9-13-7(10)12-8(11)14-9/h3-4H,1-2,5-6H2,(H4,10,11,12,13,14)

HIDE SMILES / InChI

Description

Diallylmelamine was tested in man as a gastric antisecretory agent. In these tests it was inactive. However, when this compound was administered to trained, unanesthetized dogs, it was surprisingly found to have pronounced and prolonged hypotensive activity. Diallylmelamine is an effective hypotensive agent in hypertensive dogs and rats, having a duration of action exceeding twenty-four hours from a single oral dose. It has limited efficacy in normotensive rats. Hypotensive activity of gradual onset is preceded by a latent period of up to two hours and becomes maximal six hours or more after dosing. This agent does not depress cardiac output or sympathetic vasoconstrictor activity.

Approval Year

Sample Use Guides

In Vivo Use Guide
25 mg/kg twice daily for 11 or 12 days
Route of Administration: Other
Name Type Language
DIALLYLMELAMINE
Common Name English
U-7720
Code English
NSC-4420
Code English
UPJOHN-7720
Code English
DAM
Common Name English
1,3,5-TRIAZINE-2,4,6-TRIAMINE, N2,N2-DI-2-PROPEN-1-YL-
Systematic Name English
Code System Code Type Description
ECHA (EC/EINECS)
202-096-1 PRIMARY
PUBCHEM
66682 PRIMARY
NSC
4420 PRIMARY
CAS
91-77-0 PRIMARY
EPA CompTox
DTXSID0059031 PRIMARY
FDA UNII
LGB76HFI14 PRIMARY