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Status:
Possibly Marketed Outside US
Source:
M020
(2023)
Source URL:
First approved in 2023
Source:
M020
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Possibly Marketed Outside US
Source:
M016
(2023)
Source URL:
First approved in 2023
Source:
M016
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Oleuropein is a phenylethanoid, a type of phenolic compound found in olive leaf together with other closely related compounds such as 10-hydroxyoleuropein, ligstroside, and 10-hydroxyligstroside. Oleuropein is traditionally removed from olives due to its bitterness. In preliminary laboratory research, oleuropein had activity as an agonist of the G-protein estrogen receptor. Oleuropein inhibited the enzymatic activity of mammalian target of rapamycin (mTOR), suggesting that mTOR inhibition is at least one of the reasons for the reported anti-cancer properties of oleuropein.
Status:
Possibly Marketed Outside US
Source:
M020
(2023)
Source URL:
First approved in 2023
Source:
M020
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
M017
(2023)
Source URL:
First approved in 2023
Source:
M017
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Possibly Marketed Outside US
Source:
LOWGAN by Yamanouchi Pharmaceutical
Source URL:
First approved in 2023
Source:
Slimming Patch by Guangzhou Hanhai Trading Co., Ltd
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Amosulalol is a beta- and alpha-1 adrenoceptor-blocking agent developed for the treatment of hypertension. Amosulalol does not cross blood brain barrier and does not have adverse affect on CNS system.The drug is marketed under the name Lowgan in Japan and Korea.
Status:
Possibly Marketed Outside US
Source:
BLA125734
(2023)
Source URL:
First approved in 2023
Source:
BLA125734
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Possibly Marketed Outside US
Source:
505G(a)(3)
(2024)
Source URL:
First approved in 2023
Source:
505G(a)(3)
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Propylene glycol stearate is used in is used in foods, pharmaceutical, and personal care products. Propylene glycol monostearate can be used as a lipophiic emulsifier and emulsion stabilizer in food. In food it is mainly used in cake batters, cake icings, cake shortening, margarine, oils, oleomargarine, poultry fat, whipped toppings, icecream, and yeast.
Status:
Possibly Marketed Outside US
Source:
BLA125734
(2023)
Source URL:
First approved in 2023
Source:
BLA125734
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
2′-Deoxycytidine (deoxyC) is one of the deoxy nucleosides, which after phosphorylation to dCTP is used to synthesize DNA via various DNA polymerases or reverse transcriptases. Deoxycytidine is phosphorylated by deoxycytidine kinase (dCK). This enzyme catalyzes the initial conversion of the nucleosides deoxyadenosine (dA), deoxyguanosine (dG), and deoxycytidine (dC) into their monophosphate forms, with subsequent phosphorylation to the triphosphate forms performed by additional enzymes.
Status:
Possibly Marketed Outside US
Source:
BLA125734
(2023)
Source URL:
First approved in 2023
Source:
BLA125734
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Deoxyguanosine is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of DNA. Deoxyguanosine can be converted to 8-hydroxy-deoxyguanosine (8-OHdG) due to hydroxyl radical attack at the C8 of guanine. 8-OHdG is a sensitive marker of the DNA damage This damage, if left unrepaired, has been proposed to contribute to mutagenicity and cancer promotion. Deoxyguanosine has long been recognized as a potent cytotoxic agent to cultured mammalian cells. This toxicity or inhibition of DNA synthesis by deoxyguanosine appears to be mediated by deoxyguanosine triphosphate-mediated inhibition of the enzyme ribonucleotide reductase. Purine nucleoside phosphorylase deficiency is thought to cause T-lymphocyte depletion by accumulation of deoxyguanosine and deoxyguanosine triphosphate, resulting in feedback inhibition of ribonucleotide reductase and hence DNA synthesis. Deoxyguanosine nucleoside analogs are potent antiviral agents.
Status:
Possibly Marketed Outside US
Source:
BLA125734
(2023)
Source URL:
First approved in 2023
Source:
BLA125734
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
2′-Deoxyadenosine, a pair of deoxythymidine (T) in double-stranded DNA, is a substrate of adenosine deaminase. In case of absence of this enzyme, 2′-deoxyadenosine accumulates in T lymphocytes and kills these cells resulting in a genetic disorder known as adenosine deaminase severe combined immunodeficiency disease (ADA-SCID).