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Status:
Possibly Marketed Outside US
Source:
21 CFR 355
(2011)
Source URL:
First approved in 2011
Source:
21 CFR 355
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Carvone is a monoterpene ketone that is found in several essential oils and used in the flavor industry, alternative medicine and as starting material for the asymmetric total synthesis of natural products. Carvone is produced in two enantiomeric forms: (R)-(-)-carvone, is found in mint leaves, and it is a principal contributor to the distinctive odor of mint. The other form, (S)-(+)-carvone, is found in caraway seeds. This form has a very different smell and is typically used to flavor rye bread and other Eastern European foods. S-(+)-Carvone is also used to prevent premature sprouting of potatoes during storage, being marketed in the Netherlands for this purpose under the name Talent. In the body, in vivo studies indicate that both enantiomers of carvone are mainly metabolized into dihydrocarvonic acid, carvonic acid and uroterpenolone.
Status:
Possibly Marketed Outside US
Source:
M020
(2020)
Source URL:
First approved in 2011
Source:
21 CFR 333D
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Status:
Possibly Marketed Outside US
Source:
21 CFR 358H
(2011)
Source URL:
First approved in 2011
Source:
21 CFR 358H
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
Kaydia Patch by Strong Current Enterprises Limited
Source URL:
First approved in 2011
Source:
EnBrace HR by Jaymac Pharma
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Piperine is a simple and pungent alkaloid found in the seeds of black pepper (Piper nigrum). Following its isolation and full characterization, the biological properties of piperine have been extensively studied, and piperine-like derivatives have shown an interesting range of pharmacological activities. Piperine is currently paving its way to become a privileged scaffold for the development of bioactive compounds with therapeutic application in multiple human diseases. In particular, piperine derivatives were shown to modulate the activity of several targets related to neurological disorders, including epilepsy, Parkinson's disease, depression and pain related disorders. Moreover, the efflux pump inhibitory ability of piperine and its analogues tackles important drug resistance mechanisms and may improve the clinical efficacy of antibiotic and anticancer drugs. Piperine has been found to have immunomodulatory, anti-oxidant, anti-asthmatic, anti-carcinogenic, anti-inflammatory, anti-ulcer, and anti-amoebic properties.
Status:
Possibly Marketed Outside US
Source:
M017
(2011)
Source URL:
First approved in 2011
Source:
M017
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
Healthy Bites Indoor Cat by Mark and Chappell Ltd
(2011)
Source URL:
First approved in 2011
Source:
Healthy Bites Indoor Cat by Mark and Chappell Ltd
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Status:
Possibly Marketed Outside US
Source:
21 CFR 333C
(2014)
Source URL:
First approved in 2011
Source:
M016
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Benzyl acetate is used as a fragrance ingredient and occurs in different plants and fruits, e.g., jasmine, apple, tea, plum, wine grape. It possesses a sweet and pleasant aroma, owing to which, it finds applications in personal hygiene and health care products.
Status:
Possibly Marketed Outside US
First approved in 2011
Source:
EnBrace HR by Jaymac Pharma
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Possibly Marketed Outside US
First approved in 2011
Source:
EnLyte by Jaymac Pharma
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Possibly Marketed Outside US
Source:
21 CFR 333A
(2020)
Source URL:
First approved in 2011
Source:
M020
Source URL:
Class (Stereo):
CHEMICAL (MIXED)