CREOSOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H10O2
Molecular Weight	138.1638
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC(C)=CC=C1O

InChI

InChIKey=PETRWTHZSKVLRE-UHFFFAOYSA-N

InChI=1S/C8H10O2/c1-6-3-4-7(9)8(5-6)10-2/h3-5,9H,1-2H3

HIDE SMILES / InChI

Molecular Formula	C8H10O2
Molecular Weight	138.1638
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
In vitro activity of natural phenolic compounds against fluconazole-resistant Candida species: a quantitative structure-activity relationship analysis.	2014-04	24387763
Antifungal efficacy of some natural phenolic compounds against significant pathogenic and toxinogenic filamentous fungi.	2013-10	23800587
Cross talk between keratinocytes and dendritic cells: impact on the prediction of sensitization.	2011-10	21742781
Field trial of a synthetic tsetse-repellent technology developed for the control of bovine trypanosomosis in Kenya.	2010-12-01	20980070
Characterisation and germline transmission of cultured avian primordial germ cells.	2010-11-29	21124737
Rate coefficients for the gas-phase reaction of hydroxyl radicals with 2-methoxyphenol (guaiacol) and related compounds.	2010-11-04	20919717
Characteristics of lignin from flax shives as affected by extraction conditions.	2010-10-20	21152318
Preferential inhibition by antidiarrheic 2-methoxy-4-methylphenol of Ca(2+) influx across acquired N-methyl-D-aspartate receptor channels composed of NR1/NR2B subunit assembly.	2010-08-15	20623618
Determination of Eucalyptus spp lignin S/G ratio: a comparison between methods.	2010-06	20133130
Organic extractives from Mentha spp. honey and the bee-stomach: methyl syringate, vomifoliol, terpenediol I, hotrienol and other compounds.	2010-04-22	20428087
Photochemistry of tricyclo[5.2.2.0(2,6)]undeca-4,10-dien-8-ones: an efficient general route to substituted linear triquinanes from 2-methoxyphenols. Total synthesis of (+/-)-Delta(9(12))-capnellene.	2010-03-08	20119991
Studies of the toxicological potential of capsinoids, XII: pharmacokinetic study of capsinoid-containing CH-19 Sweet extract in rats.	2010-03	20388820
Methyl 3,5-bis-[(4-hydroxy-methyl-2-methoxy-phen-oxy)meth-yl]benzoate.	2010-02-27	21580441
A multidisciplinary study of archaeological grape seeds.	2010-02	20033124
Capsaicinoids, chloropicrin and sulfur mustard: possibilities for exposure biomarkers.	2010	21833179
Capillary electrophoretic determination of selected phenolic compounds in humic substances of well waters and fertilizers.	2010	20467131
Chemical causes of the typical burnt smell after accidental fires.	2009-11	19730832
Improving the stability and antioxidant properties of sesame oil: water-soluble spray-dried emulsions from new transesterified phenolic derivatives.	2009-08-26	19653627
Volatile composition of Merlot wine from different vine water status.	2009-08-26	19627143
Protective effect and relation structure-activity of nonivamide and iododerivatives in several models of lipid oxidation.	2009-07-15	19497416
New oxidase from Bjerkandera arthroconidial anamorph that oxidizes both phenolic and nonphenolic benzyl alcohols.	2009-04	19110079
Influence of Honey on the Suppression of Human Low Density Lipoprotein (LDL) Peroxidation (In vitro).	2009-03	18955249
Non-vanillyl resiniferatoxin analogues as potent and metabolically stable transient receptor potential vanilloid 1 agonists.	2009-01-15	19135377
Reactions of tertiary phosphines with alcohols in aqueous media.	2009-01-05	19053333
Relationships between sensory descriptors, consumer acceptability and volatile flavor compounds of American dry-cured ham.	2008-11	22063590
Optimised recovery of lignin-derived phenols in a Scottish fjord by the CuO oxidation method.	2008-10	19244642
Anti-angiogenic, anti-inflammatory and anti-nociceptive activities of vanillyl alcohol.	2008-10	18958417
Smoke-derived taint in wine: the release of smoke-derived volatile phenols during fermentation of Merlot juice following grapevine exposure to smoke.	2008-08-27	18680304
2-Meth-oxy-4-methyl-phenyl 4-toluene-sulfonate.	2008-08-16	21201742
Structural analogues of homoeriodictyol as flavor modifiers. Part III: short chain gingerdione derivatives.	2008-08-13	18598048
Probing the molecular and electronic structure of capsaicin: a spectroscopic and quantum mechanical study.	2008-06-26	18507451
Stereocontrolled synthesis of polyfunctionalized cis-decalins from 2-methoxyphenols: total syntheses of (+/-)-eremopetasidione, (+/-)-3 beta-angeloyloxyfuranoeremophilane, and (+/-)-3 beta-methacryloyloxyfuranoeremophilane.	2008-04-04	18324829
Herbal compounds and toxins modulating TRP channels.	2008-03	19305789
ThermoTRP channels in nociceptors: taking a lead from capsaicin receptor TRPV1.	2008-03	19305786
Studies of the toxicological potential of capsinoids: VIII. A 13-week toxicity study of commercial-grade dihydrocapsiate in rats.	2008	19037802
Smoke-derived taint in wine: effect of postharvest smoke exposure of grapes on the chemical composition and sensory characteristics of wine.	2007-12-26	18052239
In vitro and in vivo modulation of testosterone mediated alterations in apoptosis related proteins by [6]-gingerol.	2007-12	18030663
Cough reflex and oral chemesthesis induced by capsaicin and capsiate in healthy never-smokers.	2007-10-31	17971242
The reactivity of ortho-methoxy-substituted catechol radicals with sulfhydryl groups: contribution for the comprehension of the mechanism of inhibition of NADPH oxidase by apocynin.	2007-08-01	17544376
Cytoprotective properties of phenolic antidiarrheic ingredients in cultured astrocytes and neurons of rat brains.	2007-07-12	17475240
Impact of phenolic compounds on hydrothermal oxidation of cellulose.	2007-06-11	17336951
[Role of sympathetic nerve activity and arterial endothelial function in pathogenesis of hypertension in patients with obstructive sleep apnea-hypopnea syndrome].	2007-06	17673017
A 4-alkyl-substituted analogue of guaiacol shows greater repellency to savannah tsetse (Glossina spp.).	2007-05	17404820
Predicting the biological activities of 2-methoxyphenol antioxidants: effects of dimers.	2007-04-18	17436566
Tsetse and other biting fly responses to Nzi traps baited with octenol, phenols and acetone.	2007-03	17373949
Oral administration of phenolic antidiarrheic ingredients prevents ovariectomy-induced bone loss.	2007-02-01	17078932
Antiproliferative and pro-apoptotic activity of eugenol-related biphenyls on malignant melanoma cells.	2007-01-18	17233906
Caged capsaicins: New tools for the examination of TRPV1 channels in somatosensory neurons.	2007-01-02	17154194
Vanillin production from simple phenols by wine-associated lactic acid bacteria.	2007-01	17209816
Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin.	2007	17365137

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:36:58 GMT 2025` Edited by `admin` on `Mon Mar 31 18:36:58 GMT 2025`
Record UNII	W9GW1KZG6N
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

2-METHOXY-4-METHYLPHENOL

Preferred Name

English

CREOSOL

Systematic Name

English

2-METHOXY-4-CRESOL

Systematic Name

English

P-CRESOL, 2-METHOXY-

Common Name

English

4-HYDROXY-3-METHOXY-1-METHYLBENZENE

Systematic Name

English

4-HYDROXY-3-METHOXYTOLUENE

Systematic Name

English

4-METHYLGUAIACOL

Systematic Name

English

2-METHOXY-4-METHYL-PHENOL

Systematic Name

English

2-METHOXY-4-METHYLPHENOL [FHFI]

Common Name

English

4-METHYL GUAIACOL

Systematic Name

English

4-METHYL-2-METHOXYPHENOL

Systematic Name

English

P-METHYLGUAIACOL

Common Name

English

P-CREOSOL

Common Name

English

CREOSOL [MI]

Common Name

English

FEMA NO. 2671

Code

English

NSC-4969

Code

English

METHYL GUAIACOL

Systematic Name

English

1-HYDROXY-2-METHOXY-4-METHYLBENZENE

Systematic Name

English

3-METHOXY-4-HYDROXYTOLUENE

Systematic Name

English

PHENOL, 2-METHOXY-4-METHYL-

Systematic Name

English

2-METHOXY-P- CRESOL

Common Name

English

2-METHOXY-P-CRESOL

Common Name

English

Classification Tree Code System Code

CFR

21 CFR 172.515