IANALUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 21:37:57 GMT 2025` Edited by `admin` on `Tue Apr 01 21:37:57 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	ZN2GQ3II96
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

IANALUMAB

Official Name

English

NVP-VAY736

Preferred Name

English

IANALUMAB [USAN]

Common Name

English

VAY736

Code

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS TNFRSF13C (TUMOR NECROSIS FACTOR RECEPTOR (TNFR) SUPERFAMILY MEMBER 13C, BAFFR, BAFF-R, BR3, B CELL ACTIVATING FACTOR RECEPTOR, CD268)), HOMO SAPIENS MONOCLONAL ANTIBODY; GAMMA1 HEAVY CHAIN (1-454) (HOMO SAPIEN

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN CYTOKINE RECEPTOR BAFF-R)(HUMAN MONOCLONAL CLONE NVS230512 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL CLONE NVS230512 .KAPPA.-CHAIN, DIMER

Common Name

English

VAY-736

Code

English

Ianalumab [WHO-DD]

Common Name

English

ianalumab [INN]

Common Name

English

Code System Code Type Description

USAN

JK-61

Created by admin on Tue Apr 01 21:37:57 GMT 2025 , Edited by admin on Tue Apr 01 21:37:57 GMT 2025

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SMS_ID

100000178265

Created by admin on Tue Apr 01 21:37:57 GMT 2025 , Edited by admin on Tue Apr 01 21:37:57 GMT 2025

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CAS

1831963-48-4

Created by admin on Tue Apr 01 21:37:57 GMT 2025 , Edited by admin on Tue Apr 01 21:37:57 GMT 2025

NO STRUCTURE GIVEN

CAS

1929549-92-7

Created by admin on Tue Apr 01 21:37:57 GMT 2025 , Edited by admin on Tue Apr 01 21:37:57 GMT 2025

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NCI_THESAURUS

C116788

Created by admin on Tue Apr 01 21:37:57 GMT 2025 , Edited by admin on Tue Apr 01 21:37:57 GMT 2025

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WIKIPEDIA

Ianalumab

Created by admin on Tue Apr 01 21:37:57 GMT 2025 , Edited by admin on Tue Apr 01 21:37:57 GMT 2025

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INN

10580

Created by admin on Tue Apr 01 21:37:57 GMT 2025 , Edited by admin on Tue Apr 01 21:37:57 GMT 2025

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FDA UNII

ZN2GQ3II96

Created by admin on Tue Apr 01 21:37:57 GMT 2025 , Edited by admin on Tue Apr 01 21:37:57 GMT 2025

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From	To
1_236	2_236
1_233	2_233
2_227	4_215
1_227	3_215
4_135	4_195
4_23	4_89
3_135	3_195
3_23	3_89
2_374	2_432
2_268	2_328
2_151	2_207
2_22	2_99
1_374	1_432
1_268	1_328
1_151	1_207
1_22	1_99

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_304
N	2_304

Related Record Type Details


					6K7GUD9GU3

TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 13C

INHIBITOR -> TARGET

Amount:

Related Record Type Details


					ZN2GQ3II96

IANALUMAB

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42
AMINO ACID REMOVAL	[1_454] [2_454]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL