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Details

Stereochemistry ABSOLUTE
Molecular Formula C13H16N4O6.ClH
Molecular Weight 360.75
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of LEVOFURALTADONE HYDROCHLORIDE

SMILES

Cl.[O-][N+](=O)C1=CC=C(O1)\C=N\N2C[C@H](CN3CCOCC3)OC2=O

InChI

InChIKey=PPSVFZXMDMUIGB-GSFIMPMYSA-N
InChI=1S/C13H16N4O6.ClH/c18-13-16(14-7-10-1-2-12(22-10)17(19)20)9-11(23-13)8-15-3-5-21-6-4-15;/h1-2,7,11H,3-6,8-9H2;1H/b14-7+;/t11-;/m0./s1

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C13H16N4O6
Molecular Weight 324.2893
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 1
Optical Activity UNSPECIFIED

Levofuraltadone is the nitrofurane used for the treatment of trypanosomiasis. It has been shown to be effective in mice and polyneuritis, a serious side effect of nitrofurazone therapy, is less frequent with levofuraltadone. Nevertheless, levofuraltadone is a very toxic agent and it has never been commercially produced.

Approval Year

PubMed

PubMed

TitleDatePubMed
[Comparison of drug tolerance between nitrofurazone, levofuraltadone (NF-602) and Bay 2502].
1969 Jan-Mar
[Comparison of the therapeutic tolerance of nitrofurazone, levofuraltadone and the Bay 2502 preparation].
1969 Jan-Mar

Sample Use Guides

30 mg/kg each day for 15 days followed by 10 mg/kg/day for 3 months
Route of Administration: Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:11:01 GMT 2023
Edited
by admin
on Fri Dec 15 15:11:01 GMT 2023
Record UNII
ZIA9BC2JJR
Record Status Validated (UNII)
Record Version
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Name Type Language
LEVOFURALTADONE HYDROCHLORIDE
Common Name English
FURALTADONE HYDROCHLORIDE, L-
Common Name English
LEVOFURALTADONE HCL
Common Name English
FURALTADONE HYDROCHLORIDE, (S)-
Common Name English
NF-902
Code English
(-)-5-(MORPHOLINOMETHYL)-3-((5-NITROFURFURYLIDENE)AMINO)-2-OXAZOLIDINONE HYDROCHLORIDE
Systematic Name English
2-OXAZOLIDINONE, 5-(MORPHOLINOMETHYL)-3-((5-NITROFURFURYLIDENE)AMINO)-, HYDROCHLORIDE, L-
Common Name English
Code System Code Type Description
FDA UNII
ZIA9BC2JJR
Created by admin on Fri Dec 15 15:11:01 GMT 2023 , Edited by admin on Fri Dec 15 15:11:01 GMT 2023
PRIMARY
CAS
13146-28-6
Created by admin on Fri Dec 15 15:11:01 GMT 2023 , Edited by admin on Fri Dec 15 15:11:01 GMT 2023
PRIMARY
CAS
7487-80-1
Created by admin on Fri Dec 15 15:11:01 GMT 2023 , Edited by admin on Fri Dec 15 15:11:01 GMT 2023
SUPERSEDED
PUBCHEM
9595286
Created by admin on Fri Dec 15 15:11:01 GMT 2023 , Edited by admin on Fri Dec 15 15:11:01 GMT 2023
PRIMARY
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