FURALTADONE HYDROCHLORIDE

First approved in 1959

Details

Stereochemistry	RACEMIC
Molecular Formula	C13H16N4O6.ClH
Molecular Weight	360.75
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.[O-][N+](=O)C1=CC=C(O1)\C=N\N2CC(CN3CCOCC3)OC2=O

InChI

InChIKey=PPSVFZXMDMUIGB-FJUODKGNSA-N

InChI=1S/C13H16N4O6.ClH/c18-13-16(14-7-10-1-2-12(22-10)17(19)20)9-11(23-13)8-15-3-5-21-6-4-15;/h1-2,7,11H,3-6,8-9H2;1H/b14-7+;

HIDE SMILES / InChI

Molecular Formula	C13H16N4O6
Molecular Weight	324.2893
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	1
Optical Activity	( + / - )

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13681531 | https://www.ncbi.nlm.nih.gov/pubmed/13810109

Furaltadone is a veterinary product, which is marketed for the treatment and control of salmonella infection of poultry. In 1960th was investigated the antibacterial properties of this drug against human Rhodesian sleeping sickness. In three cases treated, two were apparently curated and the third relapsed. No toxic effects attributable to the product had been observed. However, the further investigation of the furaltadone in human was not provided.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Rhodesian sleeping sickness 3 Sources: https://www.ncbi.nlm.nih.gov/pubmed/13681531	Primary	Not Provided 511	Unknown Approved Use Unknown
bacterial pneumonias 3 Sources: https://books.google.ru/books?id=gzH4DlrVpmkC&pg=PA246&lpg=PA246&dq=FURALTADONE+Altafur+Norwich+Eaton&source=bl&ots=Nw_ZEWVcQ5&sig=-ihhH1gwWntKdDQ0bY0D2VnQUQU&hl=ru&sa=X&ved=0ahUKEwj9jJStuajbAhXBFywKHdE3ADIQ6AEIKDAA#v=onepage&q=FURALTADONE%20Altafur%20Norwich%20Eaton&f=false	Curative	Approved 8583	Altafur Approved Use Unknown
bronchiolitis 3 Sources: https://books.google.ru/books?id=gzH4DlrVpmkC&pg=PA246&lpg=PA246&dq=FURALTADONE+Altafur+Norwich+Eaton&source=bl&ots=Nw_ZEWVcQ5&sig=-ihhH1gwWntKdDQ0bY0D2VnQUQU&hl=ru&sa=X&ved=0ahUKEwj9jJStuajbAhXBFywKHdE3ADIQ6AEIKDAA#v=onepage&q=FURALTADONE%20Altafur%20Norwich%20Eaton&f=false	Curative	Approved 8583	Altafur Approved Use Unknown

Sourcing

Vendor/Aggregator	ID	URL
1PlusChem LLC	1P00I7V8
A2B Chem	AI49204
AbovChem LLC	HY-B1148
AK Scientific	2419AH
AK Scientific	2420AH
AK Scientific	6804AA
Alfa Chemistry	66931
Alfa Chemistry	ACM14343716
Alfa Chemistry	ACM71662118
Ambeed	A211792
ApexBio Technology	B1764
AstaTech	C74933
Bide Pharmatech	BD131651
BioSynth	W-106526
BLD Pharm	BD131649
BLD Pharm	BD131651
BOC Sciences	139-91-3
BOC Sciences	3759-92-0
BOC Sciences	3795-88-8
Bosche Scientific	F2055
Chem Scene	CS-4752
ChemShuttle	141751
Combi-Blocks	QP-3802
Compound Cloud	9553856
Compound Cloud	9579050
eMolecules	50419818
eMolecules	511160
eMolecules	538517
eMolecules	56967780
eMolecules	76745953
eNovation Chemicals	D140192
Fluorochem	463484
Fluorochem	542109
Frontier Scientific Services	500054435
Hairui	HR110011
Hairui	HR137925
Hangzhou APIChem Technology	AC-12742
Hangzhou Yuhao Chemical Technology	HL2390
KeyOrganics	AS-74680
Lab Network	LN00241676
Lab Network	LN01292408
mcule	MCULE-1908762834
mcule	MCULE-2597584632
mcule	MCULE-4513121230
mcule	MCULE-6124791587
MedChem Express	HY-B1148
Molnova	M14296
MolPort	MolPort-001-847-047
MolPort	MolPort-003-941-410
MuseChem	I013821
MuseChem	R009598
NCI Plated 2007	186663
NCI Plated 2007	42388
NCI Plated 2007	527986
NCI Plated 2007	53270
Norris Pharm	NSZB-A230938
PI Chemicals	PI-14014
PI Chemicals	PI-14015
Ryan Scientific	Sodium_Nitroprusside
Selleck Chemicals	S4203
Sigma Aldrich	46289\|SIAL
Sigma Aldrich	F9130\|SIGMA
Sigma Aldrich	F9255\|SIGMA
Sigma Aldrich	F9380
Sigma Aldrich	F9380\|SIGMA
TargetMol	T0896
Tetrahedron	TS61818
Tetrahedron	TS79556
Tetrahedron	TS82854
TimTec	SBB057406
TimTec	ST50999663
Toronto Research Chemicals	B208000
Toronto Research Chemicals	B497335
Toronto Research Chemicals	F863400
Toronto Research Chemicals	P833605
Wonderchem	WD056AG
ZINC	ZINC000019203852	http://zinc15.docking.org/substances/ZINC000019203852
ZINC	ZINC000019203855	http://zinc15.docking.org/substances/ZINC000019203855
ZINC	ZINC000031261650	http://zinc15.docking.org/substances/ZINC000031261650
ZINC	ZINC000254518542	http://zinc15.docking.org/substances/ZINC000254518542
ZINC	ZINC000254518549	http://zinc15.docking.org/substances/ZINC000254518549

PubMed

Title	Date	PubMed
Antiprotozoals effective in vitro against the scuticociliate fish pathogen Philasterides dicentrarchi.	2002-06-03	12113305
Bactericidal activity of nitrofurans against growing and dormant Mycobacterium bovis BCG.	2000-12	11102410
The therapeutic effect of 16 antimicrobial agents on Cryptosporidium infection in mice.	1982-04	7115220

Patents

Sample Use Guides

In Vivo Use Guide

oral: 250 mg every 6 hour intravenous: 500 mg

Route of Administration: Other

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:33:47 GMT 2025` Edited by `admin` on `Mon Mar 31 18:33:47 GMT 2025`
Record UNII	37Q02H7JT2
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FURALTADONE HYDROCHLORIDE

Common Name

English

NF-269

Preferred Name

English

Furaltadone hydrochloride [WHO-DD]

Common Name

English

FURALTADONE HYDROCHLORIDE [MART.]

Common Name

English

NSC-53270

Code

English

FURALTADONE HCL

Common Name

English

5-MORPHOLINOMETHYL-3-(5-NITROFURFURYLIDINE)AMINO-2-OXAZOLIDINONE HYDROCHLORIDE

Common Name

English

NF-902 HYDROCHLORIDE

Code

English

Code System Code Type Description

PUBCHEM

9576185