U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C13H16N4O6
Molecular Weight 324.2893
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of FURALTADONE

SMILES

[O-][N+](=O)C1=CC=C(O1)\C=N\N2CC(CN3CCOCC3)OC2=O

InChI

InChIKey=YVQVOQKFMFRVGR-VGOFMYFVSA-N
InChI=1S/C13H16N4O6/c18-13-16(14-7-10-1-2-12(22-10)17(19)20)9-11(23-13)8-15-3-5-21-6-4-15/h1-2,7,11H,3-6,8-9H2/b14-7+

HIDE SMILES / InChI

Molecular Formula C13H16N4O6
Molecular Weight 324.2893
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 1
Optical Activity ( + / - )

Description

Furaltadone is a veterinary product, which is marketed for the treatment and control of salmonella infection of poultry. In 1960th was investigated the antibacterial properties of this drug against human Rhodesian sleeping sickness. In three cases treated, two were apparently curated and the third relapsed. No toxic effects attributable to the product had been observed. However, the further investigation of the furaltadone in human was not provided.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown
Curative
Altafur
Curative
Altafur

Sourcing

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
oral: 250 mg every 6 hour intravenous: 500 mg
Route of Administration: Other
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
5X4V82ZN30
Record Status Validated (UNII)
Record Version