Negalstobart

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 15:09:55 GMT 2023` Edited by `admin` on `Sat Dec 16 15:09:55 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	ZH12W2AA34
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Negalstobart

Official Name

English

Gamma4 heavy chain Homo sapiens (1-446) [VH (Homo sapiens IGHV4-39*01 (96.0%) -(IGHD) -IGHJ3*02 (100%), CDR-IMGT [10.7.12] (26-35.53-59.98-109)) (1-120)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10, G4v4 CH2 A1.3, A1.2 (CH1 (121-218), hinge 1-12 S1

Common Name

English

negalstobart [INN]

Common Name

English

Immunoglobulin G4-kappa, anti-[Homo sapiens LAG3 (lymphocyte activating 3, lymphocyte-activation 3, CD223)], Homo sapiens monoclonal antibody

Common Name

English

IBI110

Code

English

Immunoglobulin G4 [228-proline,234-alanine,235-alanine,de-C-terminal-lysine], anti-(human lymphocyte activation gene-3) (human monoclonal IBI110 γ4-chain), disulfide with human monoclonal IBI110 κ-chain, dimer

Common Name

English

IBI-110

Common Name

English

Code System Code Type Description

FDA UNII

ZH12W2AA34

Created by admin on Sat Dec 16 15:09:55 GMT 2023 , Edited by admin on Sat Dec 16 15:09:55 GMT 2023

PRIMARY

CAS

2360418-68-2

Created by admin on Sat Dec 16 15:09:55 GMT 2023 , Edited by admin on Sat Dec 16 15:09:55 GMT 2023

PRIMARY

INN

12629

Created by admin on Sat Dec 16 15:09:55 GMT 2023 , Edited by admin on Sat Dec 16 15:09:55 GMT 2023

PRIMARY

From	To
1_22	1_97
2_22	2_97
2_134	4_215
2_147	2_203
2_261	2_321
1_134	3_215
2_367	2_425
3_23	3_88
3_135	3_195
4_23	4_88
4_135	4_195
1_147	1_203
1_226	2_226
1_229	2_229
1_261	1_321
1_367	1_425

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_297
N	2_297

Related Record Type Details


					AK0JDV1ZK5

LYMPHOCYTE ACTIVATION GENE 3 PROTEIN

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					ZH12W2AA34

Negalstobart

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL