Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C20H29FN2O3 |
Molecular Weight | 363.4568 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC(CCC[18F])=CC(C(=O)NC[C@@H]2CCCN2CC=C)=C1OC
InChI
InChIKey=OABRYNHZQBZDMG-DLGGVWGKSA-N
InChI=1S/C20H29FN2O3/c1-4-10-23-11-6-8-16(23)14-22-20(24)17-12-15(7-5-9-21)13-18(25-2)19(17)26-3/h4,12-13,16H,1,5-11,14H2,2-3H3,(H,22,24)/t16-/m0/s1/i21-1
Molecular Formula | C20H29FN2O3 |
Molecular Weight | 363.4568 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Originator
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Fluorinated benzamide neuroleptics--III. Development of (S)-N-[(1-allyl-2-pyrrolidinyl)methyl]-5-(3-[18F]fluoropropyl)-2, 3-dimethoxybenzamide as an improved dopamine D-2 receptor tracer. | 1995 Apr |
|
Preliminary assessment of extrastriatal dopamine D-2 receptor binding in the rodent and nonhuman primate brains using the high affinity radioligand, 18F-fallypride. | 1999 Jul |
|
Brain imaging of 18F-fallypride in normal volunteers: blood analysis, distribution, test-retest studies, and preliminary assessment of sensitivity to aging effects on dopamine D-2/D-3 receptors. | 2002 Dec 1 |
|
PET tracers for imaging of the dopaminergic system. | 2006 |
|
18F-fallypride binding potential in patients with schizophrenia compared to healthy controls. | 2010 Sep |
|
Dopamine D3 receptor binding of (18)F-fallypride: Evaluation using in vitro and in vivo PET imaging studies. | 2015 Dec |
|
[(18)F]fallypride characterization of striatal and extrastriatal D(2/3) receptors in Parkinson's disease. | 2018 |
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:37:26 GMT 2023
by
admin
on
Fri Dec 15 15:37:26 GMT 2023
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Record UNII |
ZF3G9J6G7I
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Record Status |
Validated (UNII)
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Record Version |
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ZF3G9J6G7I
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166173-82-6
Created by
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449762
Created by
admin on Fri Dec 15 15:37:26 GMT 2023 , Edited by admin on Fri Dec 15 15:37:26 GMT 2023
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Related Record | Type | Details | ||
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TARGET->RADIOLIGAND |
Rat receptor
BINDING
Kd
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Related Record | Type | Details | ||
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ACTIVE MOIETY |